Effects of photoperiod on salsolinol‐induced prolactin secretion in goats

• Published in: Animal science journal Vol. 83; no. 5; pp. 418 - 425
• Main Authors: YAEGASHI, Tomoyoshi, JIN, Jin, SAWADA, Tatsuru, SAITO, Hayato, FÜLÖP, Ferenc, NAGY, György Miklos, HASHIZUME, Tsutomu
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01-05-2012; Blackwell Publishing Ltd
• Subjects: ambient temperature; Animal sciences; Animals; antagonists; Dopamine Antagonists - pharmacology; Female; Females; goat; Goats; Goats - physiology; Hormones; Isoquinolines - pharmacology; nannygoats; Photoperiod; PRL; prolactin; Prolactin - secretion; salsolinol; secretion; Sulpiride - pharmacology; Sun; Temperature; thyrotropin-releasing hormone; Thyrotropin-Releasing Hormone - pharmacology
• ISSN: 1344-3941; 1740-0929
• DOI: 10.1111/j.1740-0929.2011.00965.x

The aim of the present study was to clarify the relation between salsolinol (SAL)‐induced prolactin (PRL) release and photoperiod in goats. A single intravenous (i.v.) injection of SAL was given to adult female goats under short (8 h light, 16 h dark) or long (16 h light, 8 h dark) photoperiod conditions at two different ambient temperatures (20°C or 5°C), and the PRL‐releasing response to SAL was compared to that of thyrotropin‐releasing hormone (TRH) or a dopamine (DA) receptor antagonist, sulpiride. SAL, as well as TRH or sulpiride, stimulated the release of PRL promptly after each injection in both 8‐ and 16‐h daily photoperiods at 20°C (P < 0.05). The area under the response curve (AUC) of PRL for the 60‐min period after injections of saline (controls), SAL, TRH and sulpiride in the 16‐h daily photoperiod group was greater than each corresponding value in the 8‐h daily photoperiod group (P < 0.05). There were no significant differences in the AUC of PRL among the values produced after the injection of SAL, TRH and sulpiride in 16‐h daily photoperiod group; however, the values produced after the injection of TRH were smallest among the three in the 8‐h daily photoperiod group (P < 0.05). The PRL‐releasing responses to SAL, TRH and sulpiride under a short and long photoperiod condition at 5°C resembled those at 20°C. These results show that a long photoperiod highly enhances the PRL‐releasing response to SAL as well as TRH or sulpiride in either medium or low ambient temperature in goats.