Thrombosis in Inferior Vena Cava (IVC) Due to Intra-cystic Hemorrhage into a Hepatic Local Cyst with Autosomal Dominant Polycystic Kidney Disease (ADPKD)

• Published in: Internal Medicine Vol. 43; no. 3; pp. 209 - 212
• Main Authors: IGUCHI, Seitaro, KASAI, Akio, KISHIMOTO, Hidefumi, SUZUKI, Kazuo, ITO, Satoshi, OGAWA, Yusuke, NISHI, Shinichi, GEJYO, Fumitake, OHNO, Yasuhiko
• Format: Journal Article
• Language: English
• Published: Tokyo The Japanese Society of Internal Medicine 01-03-2004; Japanese Society of Internal Medicine
• Subjects: Aged; autosomal dominant polycystic kidney disease (ADPKD); Biological and medical sciences; Cysts - complications; extrinsic mechanical compression; General aspects; Hemorrhage - complications; Humans; intra-cystic hemorrhage; Kidneys; Liver Diseases - complications; localized hepatic cysts; Male; Malformations of the urinary system; Medical sciences; Nephrology. Urinary tract diseases; Polycystic Kidney, Autosomal Dominant - complications; Stress, Mechanical; thrombosis; Tomography, X-Ray Computed; Vena Cava, Inferior; Venous Thrombosis - complications; Venous Thrombosis - drug therapy; Venous Thrombosis - etiology; Kidney disease; Urinary system disease; Polycystic kidney; Liver; Cardiovascular disease; Autosome; Hemorrhage; Thrombosis; Genetic disease; Vascular disease; Medicine; extrinsic mechanical compression; intra-cystic hemorrhage; Cyst; autosomal dominant polycystic kidney disease (ADPKD); Benign neoplasm; Inferior vena cava; localized hepatic cysts
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.43.209

A 76-year-old man with autosomal dominant polycystic kidney disease (ADPKD) was admitted complaining of severe edema of bilateral lower extremities. Computed tomography (CT) of his abdomen revealed an enlarged hepatic cyst with intra-cystic hemorrhage, and massive thrombosis in the inferior vena cava (IVC). The extrinsic mechanical stress on the IVC seemed to induce thrombosis within the IVC, and the thrombosis was likely the cause of severe edema in lower extremities. In this report, we present a rare case of IVC thrombosis due to an enlarged cyst in ADPKD successful treated with anticoagulant therapy.