Management of chronic liver diseases and cirrhosis: current status and future directions
[1] Globally, the most common etiologies of CLD and cirrhosis are non-alcoholic fatty liver disease (NAFLD), followed by hepatitis B virus (HBV), hepatitis C virus (HCV), and alcohol liver disease (ALD) in 2017. [3] Despite the successful HBV vaccination plans in high endemic areas and effective ant...
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| Published in: | Chinese medical journal Vol. 133; no. 22; pp. 2647 - 2649 |
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Lippincott Williams & Wilkins
20-11-2020
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| Abstract | [1] Globally, the most common etiologies of CLD and cirrhosis are non-alcoholic fatty liver disease (NAFLD), followed by hepatitis B virus (HBV), hepatitis C virus (HCV), and alcohol liver disease (ALD) in 2017. [3] Despite the successful HBV vaccination plans in high endemic areas and effective anti-HBV and anti-HCV treatments, the age-standardized prevalence of CLD and cirrhosis caused by HBV and HCV kept rising at a rate of 9.0% and 10.2%, respectively, in the last decade (2007–2017). [...]the age-standardized prevalence of CLD and cirrhosis caused by NAFLD, leading cause of CLD and cirrhosis, increased by 23.5% within the same period. [...]lifestyle modification is still the mainstay of treatment. [7] More emerging medications, such as C-C chemokine receptor types 2 and 5 inhibitor, peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 agonist, vitamin E, and some novel drugs are being studied and potentially provide new solutions. |
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| AbstractList | [1] Globally, the most common etiologies of CLD and cirrhosis are non-alcoholic fatty liver disease (NAFLD), followed by hepatitis B virus (HBV), hepatitis C virus (HCV), and alcohol liver disease (ALD) in 2017. [3] Despite the successful HBV vaccination plans in high endemic areas and effective anti-HBV and anti-HCV treatments, the age-standardized prevalence of CLD and cirrhosis caused by HBV and HCV kept rising at a rate of 9.0% and 10.2%, respectively, in the last decade (2007–2017). [...]the age-standardized prevalence of CLD and cirrhosis caused by NAFLD, leading cause of CLD and cirrhosis, increased by 23.5% within the same period. [...]lifestyle modification is still the mainstay of treatment. [7] More emerging medications, such as C-C chemokine receptor types 2 and 5 inhibitor, peroxisome proliferator-activated receptor agonists, glucagon-like peptide-1 agonist, vitamin E, and some novel drugs are being studied and potentially provide new solutions. |
| Author | Xu, Xiao-Yuan Xu, Jing-Hang Yu, Yan-Yan |
| AuthorAffiliation | Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China |
| AuthorAffiliation_xml | – name: Department of Infectious Diseases, Peking University First Hospital, Beijing 100034, China |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32925282$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/liv.13458 10.1016/S0140-6736(19)33041-7 10.1136/gutjnl-2019-318237 10.1007/s12072-019-09970-3 10.1016/j.jhep.2019.03.004 10.1016/S0140-6736(18)32279-7 10.1001/jama.2020.2298 10.1111/liv.12958 10.1016/S2468-1253(19)30119-0 10.1016/S0140-6736(12)61425-1 10.1097/CM9.0000000000000445 10.1097/CM9.0000000000000298 10.1053/j.gastro.2020.02.058 |
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| Title | Management of chronic liver diseases and cirrhosis: current status and future directions |
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