Phase 2 Trial of Induction Gemcitabine, Oxaliplatin, and Cetuximab Followed by Selective Capecitabine-Based Chemoradiation in Patients With Borderline Resectable or Unresectable Locally Advanced Pancreatic Cancer

Purpose To evaluate, in a phase 2 study, the safety and efficacy of induction gemcitabine, oxaliplatin, and cetuximab followed by selective capecitabine-based chemoradiation in patients with borderline resectable or unresectable locally advanced pancreatic cancer (BRPC or LAPC, respectively). Method...

Full description

Saved in:

Bibliographic Details
Published in:	International journal of radiation oncology, biology, physics Vol. 88; no. 4; pp. 837 - 844
Main Authors:	Esnaola, Nestor F., MD, Chaudhary, Uzair B., MD, O'Brien, Paul, MD, Garrett-Mayer, Elizabeth, PhD, Camp, E. Ramsay, MD, Thomas, Melanie B., MD, Cole, David J., MD, Montero, Alberto J., MD, Hoffman, Brenda J., MD, Romagnuolo, Joseph, MD, Orwat, Kelly P., MD, Marshall, David T., MD
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 15-03-2014
Subjects:	Adenocarcinoma - mortality Adenocarcinoma - pathology Adenocarcinoma - therapy Adult Aged Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Capecitabine Chemoradiotherapy - adverse effects Chemoradiotherapy - methods Chemoradiotherapy - mortality CHEMOTHERAPY COMPARATIVE EVALUATIONS Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Drug Administration Schedule Female Fluorouracil - administration & dosage Fluorouracil - analogs & derivatives Hematology, Oncology and Palliative Medicine Humans Induction Chemotherapy - adverse effects Induction Chemotherapy - methods Induction Chemotherapy - mortality Male Middle Aged NEOPLASMS Organoplatinum Compounds - administration & dosage PANCREAS Pancreatic Neoplasms - mortality Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy PATIENTS Radiology RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Dosage Radiotherapy, Intensity-Modulated - methods SAFETY SURGERY
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!