Non-Uniform Bioaccumulation of Lead and Arsenic in Two Remote Regions of the Human Heart's Left Ventricle: A Post-Mortem Study

The extent of heavy-metal-induced cardiotoxicity is proportional to the levels of metal bioaccumulation, and it was previously assumed that heavy metals accumulate uniformly in the myocardium. Therefore, the aim of this study was to investigate concentrations of metals and metalloids in two distant...

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Bibliographic Details
Published in:	Biomolecules (Basel, Switzerland) Vol. 13; no. 8; p. 1232
Main Authors:	Cirovic, Ana, Orisakwe, Orish E, Cirovic, Aleksandar, Jevtic, Jovan, Tasic, Danijela, Tasic, Nebojsa
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 01-08-2023 MDPI
Subjects:	Aged Aging - metabolism Arsenic Arsenic - metabolism Arsenic - pharmacokinetics Arsenic - toxicity Atherosclerosis Autopsy Bioaccumulation Cadmium Cardiac muscle Cardiomyocytes Cardiotoxicity Cardiotoxicity - metabolism Cardiovascular disease Chronic obstructive pulmonary disease Female Gas flow Health aspects Heart failure Heart ventricle, Left Heart Ventricles - cytology Heart Ventricles - drug effects Heart Ventricles - metabolism Heart Ventricles - pathology Heavy metals Humans Hypoxia Iron Kinases Lead Lead - metabolism Lead - pharmacokinetics Lead - toxicity left ventricle Male Mass spectrometry Mass spectroscopy Mortality Myocardium post-mortem Scientific imaging Septum Ventricle Ventricular Septum - cytology Ventricular Septum - drug effects Ventricular Septum - metabolism Ventricular Septum - pathology Serbia United Kingdom > UK arsenic left ventricle lead post-mortem
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