Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin

•EMCN is a novel marker of human HSCs.•EMCN is a more specific marker of HSCs than CD34 as it can discriminate HSCs from lineage-committed HPCs. [Display omitted]

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Bibliographic Details
Published in:	Blood advances Vol. 2; no. 13; pp. 1628 - 1632
Main Authors:	Reckzeh, Kristian, Kizilkaya, Hüsün, Helbo, Alexandra Søgaard, Alrich, Montserrat Estruch, Deslauriers, André Gundersen, Grover, Amit, Rapin, Nicolas, Asmar, Fazila, Grønbæk, Kirsten, Porse, Bo, Borregaard, Niels, Vestweber, Dietmar, Nerlov, Claus, Theilgaard-Mönch, Kim
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 10-07-2018 American Society of Hematology Elsevier
Subjects:	Adult Adult Stem Cells - cytology Adult Stem Cells - metabolism Gene Expression Regulation Hematopoietic Stem Cells - cytology Hematopoietic Stem Cells - metabolism Humans Sialoglycoproteins - biosynthesis Stimulus Report
Online Access:	Get full text
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Summary:	•EMCN is a novel marker of human HSCs.•EMCN is a more specific marker of HSCs than CD34 as it can discriminate HSCs from lineage-committed HPCs. [Display omitted]
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2473-9529 2473-9537
DOI:	10.1182/bloodadvances.2018015743