Curcumin and Quercetin-Loaded Lipid Nanocarriers: Development of Omega-3 Mucoadhesive Nanoemulsions for Intranasal Administration

Curcumin (CUR) and quercetin (QU) are potential compounds for treatment of brain diseases such as neurodegenerative diseases (ND) because of their anti-inflammatory and antioxidant properties. However, low water solubility and poor bioavailability hinder their clinical use. In this context, nanotech...

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Bibliographic Details
Published in:	Nanomaterials (Basel, Switzerland) Vol. 12; no. 7; p. 1073
Main Authors:	Vaz, Gustavo Richter, Carrasco, Mariana Corrêa Falkembach, Batista, Matheus Monteiro, Barros, Paula Alice Bezerra, Oliveira, Meliza da Conceição, Muccillo-Baisch, Ana Luiza, Yurgel, Virginia Campello, Buttini, Francesca, Soares, Félix Alexandre Antunes, Cordeiro, Larissa Marafiga, Fachel, Flavia, Teixeira, Helder Ferreira, Bidone, Juliana, de Oliveira, Patrícia Diaz, Sonvico, Fabio, Dora, Cristiana Lima
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 25-03-2022 MDPI
Subjects:	Antioxidants Bioavailability Biocompatibility Biopharmaceuticals Brain Chloride Controlled release Curcumin Ethanol Fatty acids Formulations Health services Inflammation Intranasal administration Lipids Nanoemulsions Nanotechnology Nervous system Neurodegenerative diseases Penetration Pharmaceuticals Polyethylene glycol Polyphenols Quercetin Surfactants Sustained release Toxicity Viscosity Zeta potential Brazil United States > US Germany toxicity nanoemulsions quercetin intranasal administration curcumin
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