Microbial lactate utilization: enzymes, pathogenesis, and regulation

Highlights • We provide a categorization of NAD-independent lactate dehydrogenases (iLDHs). • We introduce how iLDHs are applied in industry and human life. • We summarize how lactate utilization stimulates microbial pathogenicity. • We compare the regulation mechanisms of lactate utilization in dif...

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Bibliographic Details
Published in:	Trends in microbiology (Regular ed.) Vol. 22; no. 10; pp. 589 - 599
Main Authors:	Jiang, Tianyi, Gao, Chao, Ma, Cuiqing, Xu, Ping
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-10-2014
Subjects:	Bacteria - metabolism Bacteria - pathogenicity biocatalysis biosensor Gene Expression Regulation, Bacterial Gene Expression Regulation, Enzymologic Humans Internal Medicine lactate utilization Lactic Acid - metabolism Models, Molecular NAD-independent lactate dehydrogenase pathogenesis regulation NAD-independent lactate dehydrogenase pathogenesis biosensor regulation lactate utilization biocatalysis
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Summary:	Highlights • We provide a categorization of NAD-independent lactate dehydrogenases (iLDHs). • We introduce how iLDHs are applied in industry and human life. • We summarize how lactate utilization stimulates microbial pathogenicity. • We compare the regulation mechanisms of lactate utilization in different species.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	0966-842X 1878-4380
DOI:	10.1016/j.tim.2014.05.008