The Phosphatase SHP2 Regulates the Spacing Effect for Long-Term Memory Induction

A property of long-term memory (LTM) induction is the requirement for repeated training sessions spaced over time. This augmentation of memory formation with spaced resting intervals is called the spacing effect. We now show that in Drosophila, the duration of resting intervals required for inducing...

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Bibliographic Details
Published in:	Cell Vol. 139; no. 1; pp. 186 - 198
Main Authors:	Pagani, Mario R., Oishi, Kimihiko, Gelb, Bruce D., Zhong, Yi
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 02-10-2009
Subjects:	Animals Drosophila Drosophila Proteins - metabolism Humans HUMDISEASE Learning MAP Kinase Signaling System Memory MOLNEURO Mushroom Bodies - cytology Mushroom Bodies - metabolism Neurons - metabolism Protein Tyrosine Phosphatases, Non-Receptor - metabolism Signal Transduction Transgenes HUMDISEASE MOLNEURO
Online Access:	Get full text
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