A Robust, Efficient, and Highly Enantioselective Method for Synthesis of Homopropargyl Amines

Fast, robust, selective: Copper‐catalyzed enantioselective additions of homopropargyl groups to a wide range of aldimines proceed readily and with high enantioselectivity. The catalytic method is scalable and practical, the allenylboron reagent is commercially available, and conversion into amines i...

Full description

Bibliographic Details

Published in:	Angewandte Chemie International Edition Vol. 51; no. 27; pp. 6618 - 6621
Main Authors:	Vieira, Erika M., Haeffner, Fredrik, Snapper, Marc L., Hoveyda, Amir H.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 02-07-2012 WILEY‐VCH Verlag
Subjects:	Amines - chemical synthesis Catalysis copper enantioselective catalysis homopropargyl amines N-heterocyclic carbenes Pargyline - analogs & derivatives Pargyline - chemical synthesis propargyl additions Propylamines - chemical synthesis Stereoisomerism
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!