GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approach

The majority of variation identified by genome wide association studies falls in non-coding genomic regions and is hypothesized to impact regulatory elements that modulate gene expression. Here we present a statistically rigorous software tool GREGOR (Genomic Regulatory Elements and Gwas Overlap alg...

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Bibliographic Details
Published in:	Bioinformatics Vol. 31; no. 16; pp. 2601 - 2606
Main Authors:	Schmidt, Ellen M, Zhang, Ji, Zhou, Wei, Chen, Jin, Mohlke, Karen L, Chen, Y Eugene, Willer, Cristen J
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 15-08-2015
Subjects:	Algorithms Bioinformatics Collection Computer programs Enrichment Epigenomics Genetic Variation - genetics Genetics Genome-Wide Association Study Genomics - methods Humans Loci Organ Specificity Original Papers Phenotype Programming Languages Quantitative Trait Loci Regulatory Sequences, Nucleic Acid - genetics Software
Online Access:	Get full text
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