FcγRI and FcγRIII on splenic macrophages mediate phagocytosis of anti-glycoprotein IIb/IIIa autoantibody-opsonized platelets in immune thrombocytopenia

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Bibliographic Details
Published in:Haematologica (Roma) Vol. 106; no. 1; pp. 250 - 254
Main Authors: Norris, Peter A A, Segel, George B, Burack, W Richard, Sachs, Ulrich J, Lissenberg-Thunnissen, Suzanne N, Vidarsson, Gestur, Bayat, Behnaz, Cserti-Gazdewich, Christine M, Callum, Jeannie, Lin, Yulia, Branch, Donald, Kapur, Rick, Semple, John W, Lazarus, Alan H
Format: Journal Article
Language:English
Published: Italy Fondazione Ferrata Storti 01-01-2021
Ferrata Storti Foundation
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Disclosures: Yulia Lin has received research funding from Novartis and Octapharma and consulting fees from Amgen and Pfizer. Alan H. Lazarus has patents on the use of monoclonal antibodies as replacements for IVIg and has received research funding from Rigel Pharmaceuticals Incorporated and CSL Behring. GBS, WRB, UJS, BB, SNL-T, CMC-G, GV, JC, DB, RK, and JWS do not have relevant conflicts on interest to disclose.
Contributions: AHL, GBS and PAAN conceived the study; PAAN, AHL, GBS, and R.K. designed experiments; WRB, UJS, SNL-T, GV, BB, CMC-G JC, YL, Dand JWS provided reagents; PAAN performed experiments; AHL, GB and PAAN analyzed and interpreted data; PAAN and GBS wrote the manuscript; AHL, GBS, PAAN, WRB, UJS, SNL-T, GV, JC, RK and JWS edited the manuscript.
ISSN:0390-6078
1592-8721
DOI:10.3324/haematol.2020.248385