Geographic and temporal genetic patterns of Aedes aegypti populations in Rio de Janeiro, Brazil

Summary Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three‐month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2...

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Published in:Tropical medicine & international health Vol. 11; no. 8; pp. 1276 - 1285
Main Authors: Da Costa‐Ribeiro, Magda C. V., Lourenço‐de‐Oliveira, Ricardo, Failloux, Anna‐Bella
Format: Journal Article
Language:English
Published: Oxford, UK Blackwell Publishing Ltd 01-08-2006
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Abstract Summary Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three‐month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high FST values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city. Rio de Janeiro est considéré comme le site d'entrée le plus important du virus de la dengue au Brésil. Nous avons utilisé des marqueurs d'isoenzymes pour investiguer la structure génétique du moustique vecteur Aedes aegypti, échantillonné sur des intervalles de 3 mois dans 14 districts de Rio de Janeiro de décembre 2002 à décembre 2003. Nous avons détecté des niveaux de différentiation génétique très élevés i.e. des valeurs élevées de FST avec des valeurs de P significatives et une tendance de persistance tout le long de l'année. Ces espèces ne profitent pas de la voie routière ou du chemin de fer pour se disperser. La structuration génétique était plus importante en saison pluvieuse, ce qui suggère une faible dispersion de Ae. aegypti durant cette période de l'année où toutes les épidémies de dengue ont été rapportées dans la ville. Rio de Janeiro se considera el punto de entrada más importante del virus del dengue en Brasil. Utilizando marcadores isoenzimáticos, hemos investigado la estructura genética del vector, elmosquito Aedes aegypti, recogido en intervalos de tres meses en 14 distritos de Río de Janeiro, entre diciembre 2002 y diciembre 2003. Hemos detectado unos altos niveles de diferenciación genética (es decir, valores altos de FST y valores p significativos) que tendían a persistir durante el año. Las especies no aprovechan las carreteras y vías ferroviarias para dispersarse. La estructuración genética fue mayor durante la época de lluvias, sugiriendo una baja dispersión de Ae. aegypti durante esta época del año, cuando se han reportado todas las epidemias de dengue en la ciudad.
AbstractList Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three-month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high F(ST) values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city.
Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three‐month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high F ST values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city. Rio de Janeiro est considéré comme le site d'entrée le plus important du virus de la dengue au Brésil. Nous avons utilisé des marqueurs d'isoenzymes pour investiguer la structure génétique du moustique vecteur Aedes aegypti , échantillonné sur des intervalles de 3 mois dans 14 districts de Rio de Janeiro de décembre 2002 à décembre 2003. Nous avons détecté des niveaux de différentiation génétique très élevés i.e. des valeurs élevées de F ST avec des valeurs de P significatives et une tendance de persistance tout le long de l'année. Ces espèces ne profitent pas de la voie routière ou du chemin de fer pour se disperser. La structuration génétique était plus importante en saison pluvieuse, ce qui suggère une faible dispersion de Ae. aegypti durant cette période de l'année où toutes les épidémies de dengue ont été rapportées dans la ville. Rio de Janeiro se considera el punto de entrada más importante del virus del dengue en Brasil. Utilizando marcadores isoenzimáticos, hemos investigado la estructura genética del vector, elmosquito A edes aegypti , recogido en intervalos de tres meses en 14 distritos de Río de Janeiro, entre diciembre 2002 y diciembre 2003. Hemos detectado unos altos niveles de diferenciación genética (es decir, valores altos de F ST y valores p significativos) que tendían a persistir durante el año. Las especies no aprovechan las carreteras y vías ferroviarias para dispersarse. La estructuración genética fue mayor durante la época de lluvias, sugiriendo una baja dispersión de Ae. aegypti durante esta época del año, cuando se han reportado todas las epidemias de dengue en la ciudad.
Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three-month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high F ST values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city. [PUBLICATION ABSTRACT]
Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three-month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high F sub(ST) values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city.
Summary Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of the mosquito vector Aedes aegypti sampled at three‐month intervals in 14 districts in Rio de Janeiro from December 2002 to December 2003. We detected high levels of genetic differentiation (i.e. high FST values and significant P values), which tended to persist throughout the year. The species does not take advantage of routes and railways to disperse. Genetic structuring was higher in the rainy season, suggesting low dispersion of Ae. aegypti at this time of year when all dengue epidemics have been reported in the city. Rio de Janeiro est considéré comme le site d'entrée le plus important du virus de la dengue au Brésil. Nous avons utilisé des marqueurs d'isoenzymes pour investiguer la structure génétique du moustique vecteur Aedes aegypti, échantillonné sur des intervalles de 3 mois dans 14 districts de Rio de Janeiro de décembre 2002 à décembre 2003. Nous avons détecté des niveaux de différentiation génétique très élevés i.e. des valeurs élevées de FST avec des valeurs de P significatives et une tendance de persistance tout le long de l'année. Ces espèces ne profitent pas de la voie routière ou du chemin de fer pour se disperser. La structuration génétique était plus importante en saison pluvieuse, ce qui suggère une faible dispersion de Ae. aegypti durant cette période de l'année où toutes les épidémies de dengue ont été rapportées dans la ville. Rio de Janeiro se considera el punto de entrada más importante del virus del dengue en Brasil. Utilizando marcadores isoenzimáticos, hemos investigado la estructura genética del vector, elmosquito Aedes aegypti, recogido en intervalos de tres meses en 14 distritos de Río de Janeiro, entre diciembre 2002 y diciembre 2003. Hemos detectado unos altos niveles de diferenciación genética (es decir, valores altos de FST y valores p significativos) que tendían a persistir durante el año. Las especies no aprovechan las carreteras y vías ferroviarias para dispersarse. La estructuración genética fue mayor durante la época de lluvias, sugiriendo una baja dispersión de Ae. aegypti durante esta época del año, cuando se han reportado todas las epidemias de dengue en la ciudad.
Author Da Costa‐Ribeiro, Magda C. V.
Failloux, Anna‐Bella
Lourenço‐de‐Oliveira, Ricardo
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Issue 8
Keywords Isozyme
Arthropoda
Insecta
Culicidae
Genetics
Tropical medicine
Aedes aegypti
Invertebrata
Diptera
genetic structure
Rio de Janeiro
isoenzymes
Language English
License CC BY 4.0
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
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Snippet Summary Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic...
Rio de Janeiro is considered as the most important entry point for dengue viruses in Brazil. Using isoenzyme markers, we investigated the genetic structure of...
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SubjectTerms Aedes - enzymology
Aedes - genetics
Aedes aegypti
Animals
Biological and medical sciences
Brazil - epidemiology
Dengue - epidemiology
Dengue - transmission
estructura genética
General aspects
Genetic markers
genetic structure
Genotype
Heterozygote
Humans
Insect Vectors - enzymology
Insect Vectors - genetics
isoenzimas
isoenzymes
Life Sciences
Medical sciences
Microbiology and Parasitology
Polymorphism, Genetic - genetics
Population genetics
Rain
Rio de Janeiro
Río de Janeiro
structure génétique
Time Factors
Tropical diseases
Urban Health
Title Geographic and temporal genetic patterns of Aedes aegypti populations in Rio de Janeiro, Brazil
URI https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-3156.2006.01667.x
https://www.ncbi.nlm.nih.gov/pubmed/16903890
https://www.proquest.com/docview/215507028
https://search.proquest.com/docview/19837023
https://search.proquest.com/docview/68743042
https://pasteur.hal.science/pasteur-01697454
Volume 11
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