Pertussis resurgence: waning immunity and pathogen adaptation - two sides of the same coin

Pertussis or whooping cough has persisted and resurged in the face of vaccination and has become one of the most prevalent vaccine-preventable diseases in Western countries. The high circulation rate of Bordetella pertussis poses a threat to infants that have not been (completely) vaccinated and for...

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Bibliographic Details
Published in:	Epidemiology and infection Vol. 142; no. 4; pp. 685 - 694
Main Authors:	Mooi, F R, Van Der Maas, N A T, De Melker, H E
Format:	Journal Article
Language:	English
Published:	England Cambridge University Press 01-04-2014
Subjects:	Adaptation Amino Acid Sequence Antigens Bordetella pertussis - immunology Bordetella pertussis - pathogenicity Communicable Diseases, Emerging Epidemics Genes Humans Infections Molecular Sequence Data Mutation Pathogens Pertussis Pertussis Toxin - chemistry Pertussis Toxin - immunology Pertussis Vaccine - immunology Proteins Review Sequence Alignment Vaccines Whooping Cough
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