A voltammetric sensor based on mixed proton-electron conducting composite including metal-organic framework JUK-2 for determination of citalopram

• Published in: Mikrochimica acta (1966) Vol. 188; no. 6; p. 184
• Main Authors: Madej, Maria, Matoga, Dariusz, Skaźnik, Klaudia, Porada, Radosław, Baś, Bogusław, Kochana, Jolanta
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01-06-2021; Springer; Springer Nature B.V
• Subjects: Analytical Chemistry; Antidepressants; Biological properties; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Conduction; Conductors; Diffraction; Electric properties; Electrochemical analysis; Electrochemical impedance spectroscopy; Fourier transforms; Glassy carbon; Gold; Infrared spectroscopy; Manganese; Metal-organic frameworks; Microengineering; Morphology; Multi wall carbon nanotubes; Nanochemistry; Nanocomposites; Nanoparticles; Nanotechnology; Nanotubes; Original Paper; Sensors; Spectrum analysis; Voltammetry; X ray powder diffraction; X-rays; Metal-organic framework; Mixed ion-electron conductor; Electrochemical sensor; Multi-walled carbon nanotubes; Gold nanoparticles; Citalopram
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-021-04835-9

A voltammetric sensor has been developed based on glassy carbon electrode (GCE) modification with nanocomposite consisting of manganese-based metal-organic framework (JUK-2), multi-walled carbon nanotubes (MWCNTs), and gold nanoparticles (AuNPs) for detection of citalopram (CIT). The composition and morphology of JUK-2-MWCNTs-AuNPs/GCE were characterized by X-ray powder diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), energy dispersion spectroscopy (EDS), and scanning electron microscopy (SEM). The electrochemical properties investigated using electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) indicated that the fabricated hybrid material exhibits the properties of mixed ion-electron conductor (MIEC). Using staircase voltammetry (SCV), under optimized conditions, the fabricated sensor shows a linear response in three CIT concentration ranges, 0.05–1.0, 1.0–10.0 and 15.0–115.0 μmol L
−1
, with a detection limit of 0.011 μmol L
−1
. The JUK-2-MWCNTs-AuNPs/GCE was successfully employed for the determination of CIT in pharmaceutical, environmental waters, and biological samples with satisfactory recoveries (98.6–104.8%).
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