Efficacy and safety of GLP-1 receptor agonists as add-on to SGLT2 inhibitors in type 2 diabetes mellitus: A meta-analysis

GLP-1 receptor agonists (GLP-1RA) and SGLT2 inhibitors (SGLT2i) have been associated with improved glycemic control, body weight loss and favorable changes in cardiovascular risk factors and outcomes. We conducted a systematic review and meta-analysis to evaluate the effects of the addition of GLP-1...

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Bibliographic Details
Published in:	Scientific reports Vol. 9; no. 1; pp. 19351 - 8
Main Authors:	Castellana, Marco, Cignarelli, Angelo, Brescia, Francesco, Perrini, Sebastio, Natalicchio, Annalisa, Laviola, Luigi, Giorgino, Francesco
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 18-12-2019 Nature Publishing Group
Subjects:	692/163/2743/137/773 692/699/2743/137/773 Blood pressure Blood Pressure - drug effects Body weight Body Weight - drug effects Diabetes Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - drug therapy Glucagon-Like Peptide-1 Receptor - agonists Glycated Hemoglobin - metabolism Health risk assessment Health risks Humanities and Social Sciences Humans Lipids Meta-analysis multidisciplinary Randomized Controlled Trials as Topic Risk factors Science Science (multidisciplinary) Sodium-Glucose Transporter 2 Inhibitors - adverse effects Sodium-Glucose Transporter 2 Inhibitors - pharmacology Sodium-Glucose Transporter 2 Inhibitors - therapeutic use Systole - drug effects Treatment Outcome
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