Functional expression of novel human and murine AKR1B genes

The Aldo Keto Reductases (AKRs) are a superfamily of enzymes that catalyze the reduction of biogenic and xenobiotic aldehydes and ketones. AKR1B family has 2 known members in humans and 3 in rodents. Two novel gene loci, hereafter referred to as AKR1B15 in human and Akr1b16 in mouse have been predic...

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Bibliographic Details
Published in:	Chemico-biological interactions Vol. 191; no. 1; pp. 177 - 184
Main Authors:	Salabei, Joshua K., Li, Xiao-Ping, Petrash, J. Mark, Bhatnagar, Aruni, Barski, Oleg A.
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 30-05-2011
Subjects:	AKR1B15 Akr1b16 Aldehyde aldehydes Aldo Keto Reductase Amino Acid Sequence Animals bacteria Bacteria - cytology Cercopithecus aethiops Cloning, Molecular complementary DNA COS Cells enzyme activity enzymes eyes Gene expression Gene Expression Regulation, Enzymologic genes Genetic Loci - genetics Genome, Human - genetics heart Humans ketones loci messenger RNA Mice Molecular Sequence Data open reading frames Oxidoreductases Acting on Aldehyde or Oxo Group Donors - chemistry Oxidoreductases Acting on Aldehyde or Oxo Group Donors - genetics Oxidoreductases Acting on Aldehyde or Oxo Group Donors - metabolism proteins RNA, Messenger - genetics RNA, Messenger - metabolism RT-PCR sequence analysis spleen testes Aldo Keto Reductase Gene expression Aldehyde AKR1B15 RT-PCR Akr1b16
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