Non-Invasive Radiofrequency Field Treatment of 4T1 Breast Tumors Induces T-cell Dependent Inflammatory Response

Previous work using non-invasive radiofrequency field treatment (RFT) in cancer has demonstrated its therapeutic potential as it can increase intratumoral blood perfusion, localization of intravenously delivered drugs, and promote a hyperthermic intratumoral state. Despite the well-known immunologic...

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Bibliographic Details
Published in:	Scientific reports Vol. 8; no. 1; pp. 3474 - 9
Main Authors:	Newton, Jared M., Flores-Arredondo, Jose H., Suki, Sarah, Ware, Matthew J., Krzykawska-Serda, Martyna, Agha, Mahdi, Law, Justin J., Sikora, Andrew G., Curley, Steven A., Corr, Stuart J.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22-02-2018 Nature Publishing Group Nature Portfolio
Subjects:	13/1 13/106 13/21 13/31 13/51 14 14/1 14/34 59 631/250 631/67 639/166 64 Animal models Animals Breast cancer Breast Neoplasms - blood Breast Neoplasms - immunology Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Cancer CD4 antigen CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - radiation effects CD8 antigen CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - radiation effects Chemokines Cytokines Cytokines - blood Female Humanities and Social Sciences Humans Hyperthermia Hyperthermia, Induced Immunomodulation Immunosuppressive agents Inflammation Localization Lymphocytes Lymphocytes T Mammary Neoplasms, Experimental - immunology Mammary Neoplasms, Experimental - pathology Mammary Neoplasms, Experimental - radiotherapy Mice multidisciplinary Perfusion Radiofrequency Therapy Science Science (multidisciplinary) Solid tumors T-Lymphocytes - immunology T-Lymphocytes - radiation effects Tumors
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