High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis

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Published in:	Blood cancer journal (New York) Vol. 12; no. 9; pp. 128 - 3
Main Authors:	Khwaja, Jahanzaib, Bomsztyk, Joshua, Mahmood, Shameem, Wisniowski, Brendan, Shah, Raakhee, Tailor, Anish, Yong, Kwee, Popat, Rakesh, Rabin, Neil, Kyriakou, Charalampia, Sive, Jonathan, Esposti, Simona Degli, Larkin, Daniel F. P., Worthington, Sarah, Hart, Alyse, Dowling, Emma, Correia, Nuno, Bygrave, Ceri, Rydzewski, Andrzej, Jamroziak, Krzysztof, Wechalekar, Ashutosh D.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 05-09-2022 Springer Nature B.V Nature Publishing Group
Subjects:	631/67/1059/2325 692/699/1541/1990/804 Antibodies, Monoclonal, Humanized Biomedical and Life Sciences Biomedicine Bortezomib Cancer Research Correspondence Hematology Humans Immunoglobulin Light-chain Amyloidosis - drug therapy Multiple Myeloma Neoplasm Recurrence, Local Oncology
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ArticleNumber	128
Author	Esposti, Simona Degli Shah, Raakhee Khwaja, Jahanzaib Bygrave, Ceri Jamroziak, Krzysztof Wisniowski, Brendan Rabin, Neil Rydzewski, Andrzej Hart, Alyse Bomsztyk, Joshua Sive, Jonathan Wechalekar, Ashutosh D. Worthington, Sarah Tailor, Anish Popat, Rakesh Larkin, Daniel F. P. Mahmood, Shameem Kyriakou, Charalampia Yong, Kwee Dowling, Emma Correia, Nuno
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Cites_doi	10.1016/S1470-2045(19)30788-0 10.1111/bjh.17636 10.1016/j.kint.2017.05.004 10.1007/s40123-020-00280-8 10.1182/blood-2021-151365 10.1080/13506129.2020.1868810
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References	Zhang, Godara, Pan, Toskic, Fogaren, Sborov (CR2) 2021; 138 Palladini, Schönland, Sanchorawala, Kumar, Wechalekar, Hegenbart (CR4) 2021; 28 Farooq, Degli Esposti, Popat, Thulasi, Lonial, Nooka (CR5) 2020; 9 Ravichandran, Cohen, Law, Sachchithanantham, Mahmood, Foard (CR6) 2021; 194 Rezk, Lachmann, Fontana, Sachchithanantham, Mahmood, Petrie (CR3) 2017; 92 Lonial, Lee, Badros, Trudel, Nooka, Chari (CR1) 2020; 21 Y Zhang (717_CR2) 2021; 138 AV Farooq (717_CR5) 2020; 9 S Ravichandran (717_CR6) 2021; 194 S Lonial (717_CR1) 2020; 21 T Rezk (717_CR3) 2017; 92 G Palladini (717_CR4) 2021; 28
References_xml	– volume: 21 start-page: 207 year: 2020 end-page: 21 ident: CR1 article-title: Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study publication-title: Lancet Oncol doi: 10.1016/S1470-2045(19)30788-0 contributor: fullname: Chari – volume: 194 start-page: 587 year: 2021 end-page: 97 ident: CR6 article-title: Haematologic responses and survival do not significantly decrease with subsequent lines of therapy in systemic immunoglobulin light chain amyloidosis: results from an analysis of real-world longitudinal data publication-title: Br J Haematol doi: 10.1111/bjh.17636 contributor: fullname: Foard – volume: 92 start-page: 1476 year: 2017 end-page: 83 ident: CR3 article-title: Prolonged renal survival in light chain amyloidosis: speed and magnitude of light chain reduction is the crucial factor publication-title: Kidney Int doi: 10.1016/j.kint.2017.05.004 contributor: fullname: Petrie – volume: 9 start-page: 889 year: 2020 end-page: 911 ident: CR5 article-title: Corneal epithelial findings in patients with multiple myeloma treated with antibody-drug conjugate belantamab mafodotin in the pivotal, randomized, DREAMM-2 study publication-title: Ophthalmol Ther doi: 10.1007/s40123-020-00280-8 contributor: fullname: Nooka – volume: 138 start-page: 1670 issue: Suppl 1 year: 2021 ident: CR2 article-title: Belantamab mafadotin in patients with relapsed/refractory AL amyloidosis with myeloma publication-title: Blood doi: 10.1182/blood-2021-151365 contributor: fullname: Sborov – volume: 28 start-page: 1 year: 2021 end-page: 2 ident: CR4 article-title: Clarification on the definition of complete haematologic response in light-chain (AL) amyloidosis publication-title: Amyloid doi: 10.1080/13506129.2020.1868810 contributor: fullname: Hegenbart – volume: 21 start-page: 207 year: 2020 ident: 717_CR1 publication-title: Lancet Oncol doi: 10.1016/S1470-2045(19)30788-0 contributor: fullname: S Lonial – volume: 92 start-page: 1476 year: 2017 ident: 717_CR3 publication-title: Kidney Int doi: 10.1016/j.kint.2017.05.004 contributor: fullname: T Rezk – volume: 138 start-page: 1670 issue: Suppl 1 year: 2021 ident: 717_CR2 publication-title: Blood doi: 10.1182/blood-2021-151365 contributor: fullname: Y Zhang – volume: 9 start-page: 889 year: 2020 ident: 717_CR5 publication-title: Ophthalmol Ther doi: 10.1007/s40123-020-00280-8 contributor: fullname: AV Farooq – volume: 28 start-page: 1 year: 2021 ident: 717_CR4 publication-title: Amyloid doi: 10.1080/13506129.2020.1868810 contributor: fullname: G Palladini – volume: 194 start-page: 587 year: 2021 ident: 717_CR6 publication-title: Br J Haematol doi: 10.1111/bjh.17636 contributor: fullname: S Ravichandran
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Title	High response rates with single-agent belantamab mafodotin in relapsed systemic AL amyloidosis
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