High doses of epoetin do not lower mortality and cardiovascular risk among elderly hemodialysis patients with diabetes

A randomized trial had suggested that high doses of erythropoiesis-stimulating agents (ESAs) might increase the risk of cardiovascular outcomes in predialysis diabetic patients. To evaluate this risk in diabetic patients receiving dialysis, we used data from 35,593 elderly Medicare patients on hemod...

Full description

Saved in:

Bibliographic Details
Published in:	Kidney international Vol. 80; no. 6; pp. 663 - 669
Main Authors:	Zhang, Yi, Thamer, Mae, Kaufman, James S., Cotter, Dennis J., Hernán, Miguel A.
Format:	Journal Article
Language:	English
Published:	Basingstoke Elsevier Inc 01-09-2011 Nature Publishing Group Elsevier Limited
Subjects:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiovascular Diseases - etiology cardiovascular outcomes Composite materials Databases, Factual diabetes Diabetes mellitus Diabetic Cardiomyopathies - etiology Diabetic Nephropathies - mortality Diabetic Nephropathies - therapy Dialysis Drugs Elderly Emergency and intensive care: renal failure. Dialysis management epoetin Erythropoietin - administration & dosage Erythropoietin - adverse effects Female Hematinics - administration & dosage Hematinics - adverse effects hemodialysis Humans Intensive care medicine Kidney Male marginal structural modeling Medical sciences Medicare Mortality Nephrology. Urinary tract diseases Recombinant Proteins - administration & dosage Recombinant Proteins - adverse effects Renal Dialysis - adverse effects Renal Dialysis - methods Renal Dialysis - mortality Risk Factors United States United States marginal structural modeling epoetin hemodialysis mortality cardiovascular outcomes diabetes Endocrinopathy Human Nephrology Prognosis Hemodialysis Diabetes mellitus Mortality Cardiovascular disease Epidemiology Modeling Urology Extrarenal dialysis Cardiovascular risk Circulatory system High dose Elderly
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!