Monovalerin and trivalerin increase brain acetic acid, decrease liver succinic acid, and alter gut microbiota in rats fed high-fat diets

Purpose Short-chain fatty acids (SCFA) are known for their anti-inflammatory properties and may also prevent against the development of metabolic diseases. This study investigated possible effects of two valeric acid esters, monovalerin (MV) and trivalerin (TV) in rats fed high-fat diets. Methods Fo...

Full description

Saved in:

Bibliographic Details
Published in:	European journal of nutrition Vol. 58; no. 4; pp. 1545 - 1560
Main Authors:	Nguyen, Thao Duy, Prykhodko, Olena, Fåk Hållenius, Frida, Nyman, Margareta
Format:	Journal Article
Language:	English
Published:	Berlin/Heidelberg Springer Berlin Heidelberg 01-06-2019 Springer Nature B.V
Subjects:	Acetic acid Acetic Acid - metabolism Animals Annan teknik Anti-inflammatory agents Bacteroidetes Biomarkers Blood Brain - drug effects Brain - metabolism Chemistry Chemistry and Materials Science Diet Diet, High-Fat Dietary supplements Engineering and Technology Esters Fatty acids Food Engineering Gastrointestinal Microbiome - drug effects High density lipoprotein High fat diet Inflammation Intestinal microflora Lipopolysaccharide-binding protein Liver Liver - drug effects Liver - metabolism Livsmedelsteknik Low density lipoprotein Low fat diet Male Metabolites Microbiota Models, Animal Nutrient deficiency Nutrition Original Contribution Other Engineering and Technologies Pentanoic Acids - pharmacology Rats Rats, Wistar Rodents Succinic acid Succinic Acid - metabolism Teknik Valeric acid Valeric acid Succinic acid Acetic acid Caecal microbiota SCFA
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!