Gut eradication of VIM-1 producing ST9 Klebsiella oxytoca after fecal microbiota transplantation for diarrhea caused by a Clostridium difficile hypervirulent R027 strain

• Published in: Diagnostic microbiology and infectious disease Vol. 86; no. 4; pp. 470 - 471
• Main Authors: García-Fernández, Sergio, Morosini, María-Isabel, Cobo, Marta, Foruny, José Ramón, López-Sanromán, Antonio, Cobo, Javier, Romero, José, Cantón, Rafael, del Campo, Rosa
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-12-2016
• Subjects: beta-Lactamases - secretion; Carbapenemase eradication; Carrier State - therapy; Clostridium difficile; Clostridium difficile - isolation & purification; Clostridium difficile infection; Diarrhea; Eco-evo strategy; Enterocolitis, Pseudomembranous - therapy; Fecal Microbiota Transplantation; Female; Gastrointestinal Tract - microbiology; Humans; Infectious Disease; Internal Medicine; Klebsiella Infections - therapy; Klebsiella oxytoca; Klebsiella oxytoca - enzymology; Klebsiella oxytoca - isolation & purification; Multidrug resistant bacteria; Eco-evo strategy; Multidrug resistant bacteria; Clostridium difficile infection; Fecal microbiota transplantation; Carbapenemase eradication
• ISSN: 0732-8893; 1879-0070
• DOI: 10.1016/j.diagmicrobio.2016.09.004

Abstract We report the fecal carriage eradication of a VIM-1-producing ST9 Klebsiella oxytoca strain in a pluripathological 84-year-old woman after fecal microbiota transplantation to control relapsing R027 hypervirulent Clostridium difficile infections. The donor was her son, in which the absence of fecal carbapenemase-producing bacteria was corroborated.