Genetic isolation of stem cell-derived pacemaker-nodal cardiac myocytes

Dysfunction of the cardiac pacemaker tissues due to genetic defects, acquired diseases, or aging results in arrhythmias. When arrhythmias occur, artificial pacemaker implants are used for treatment. However, the numerous limitations of electronic implants have prompted studies of biological pacemake...

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Bibliographic Details
Published in:	Molecular and cellular biochemistry Vol. 383; no. 1-2; pp. 161 - 171
Main Authors:	Hashem, Sherin I., Claycomb, William C.
Format:	Journal Article
Language:	English
Published:	Boston Springer US 01-11-2013 Springer Springer Nature B.V
Subjects:	Aggregates Aging Animals Araneae Arrhythmia Atrioventricular Node - cytology Biochemistry Biological Clocks - genetics Biomedical and Life Sciences Blotting, Western Calcium - metabolism Cardiac arrhythmia Cardiology Cardiomyocytes Cell Aggregation - genetics Cell culture Cell Differentiation - genetics Cell Line Cell morphology Cell Separation - methods Connexins - metabolism Embryoid Bodies - cytology Embryoid Bodies - metabolism Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Enhancer Elements, Genetic - genetics Gene Expression Profiling Gene Expression Regulation Genetics Homeodomain Proteins - metabolism Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels - metabolism Life Sciences Medical Biochemistry Mice Myocytes, Cardiac - cytology Myocytes, Cardiac - metabolism Oncology Sinoatrial Node - cytology Stem cells Embryonic stem cell Sinoatrial Embryoid body Atrioventricular Pacemaker
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