Filariasis in Africa—treatment challenges and prospects

Lymphatic filariasis (LF) and onchocerciasis are parasitic nematode infections that are responsible for a major disease burden in the African continent. Disease symptoms are induced by the immune reactions of the host, with lymphoedema and hydrocoele in LF, and dermatitis and ocular inflammation in...

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Bibliographic Details
Published in:	Clinical microbiology and infection Vol. 17; no. 7; pp. 977 - 985
Main Authors:	Hoerauf, A., Pfarr, K., Mand, S., Debrah, A.Y., Specht, S.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Elsevier Ltd 01-07-2011 Blackwell Publishing Ltd Elsevier Limited
Subjects:	Africa - epidemiology Albendazole Albendazole - adverse effects Albendazole - pharmacology Albendazole - therapeutic use Animals AWOL diethylcarbamazine DOLF Elephantiasis, Filarial - drug therapy Elephantiasis, Filarial - epidemiology filarial diseases Filaricides - pharmacology Filaricides - therapeutic use Humans ivermectin Ivermectin - adverse effects Ivermectin - pharmacology Ivermectin - therapeutic use Nematoda Onchocerca volvulus Onchocerca volvulus - microbiology Onchocerca volvulus - pathogenicity Onchocerca volvulus - physiology Onchocerciasis - drug therapy Onchocerciasis - epidemiology Symbiosis treatment and research aspects Wolbachia Wolbachia - physiology Wuchereria bancrofti Wuchereria bancrofti - microbiology Wuchereria bancrofti - pathogenicity Wuchereria bancrofti - physiology Africa Albendazole DOLF Wolbachia treatment and research aspects filarial diseases AWOL ivermectin diethylcarbamazine
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