Long-term results of Taiwan Pediatric Oncology Group studies 1997 and 2002 for childhood acute lymphoblastic leukemia

The long-term outcome of 1390 children with acute lymphoblastic leukemia (ALL), treated in two successive clinical trials (Taiwan Pediatric Oncology Group (TPOG)-ALL-97 and TPOG-ALL-2002) between 1997 and 2007, is reported. The event-free survival improved significantly ( P =0.0004) over this period...

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Published in:	Leukemia Vol. 24; no. 2; pp. 397 - 405
Main Authors:	Liang, D-C, Yang, C-P, Lin, D-T, Hung, I-J, Lin, K-H, Chen, J-S, Hsiao, C-C, Chang, T-T, Peng, C-T, Lin, M-T, Chang, T-K, Jaing, T-H, Liu, H-C, Wang, L-Y, Yeh, T-C, Jou, S-T, Lu, M-Y, Cheng, C-N, Sheen, J-M, Chiou, S-S, Wu, K-H, Hung, G-Y, Chen, R-L, Chen, S-H, Cheng, S-N, Chang, Y-H, Chen, B-W, Ho, W-L, Wang, J-L, Lin, S-T, Hsieh, Y-L, Wang, S-C, Chang, H-H, Yang, Y-L, Huang, F-L, Chang, C-Y, Chang, W-H, Lin, K-S
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-02-2010 Nature Publishing Group
Subjects:	Acute lymphoblastic leukemia Acute lymphocytic leukemia Adolescent Antineoplastic Combined Chemotherapy Protocols - therapeutic use Asparaginase Cancer Research Care and treatment Child Child, Preschool Children Chromosome Aberrations Clinical trials Combined Modality Therapy Cranial Irradiation Critical Care Medicine Diagnosis educational-report Etoposide Female Follow-Up Studies Health aspects Health risks Hematology Humans Immunophenotyping Infant Intensive Internal Medicine Irradiation L-asparaginase Leukemia Leukocytes Lymphatic leukemia Lymphocytes T Male Medicine Medicine & Public Health Multivariate analysis Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - pathology Neoplasm Recurrence, Local - therapy Neoplasm, Residual Neoplasms, Second Primary - genetics Neoplasms, Second Primary - pathology Neoplasms, Second Primary - therapy Oncology Patients Pediatrics Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy Prednisolone Prognosis Quality of life Radiation Remission Remission Induction Risk Risk Factors Runx1 protein Skull Survival Rate Taiwan Time Factors Treatment Outcome Vincristine Taiwan treatment results acute lymphoblastic leukemia children
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