Osteogenic differentiation of human mesenchymal stem cells in the absence of osteogenic supplements: A surface-roughness gradient study

[Display omitted] The use of biomaterials to direct osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of osteogenic supplements is thought to be part of the next generation of orthopedic implants. We previously engineered surface-roughness gradients of average roughne...

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Bibliographic Details
Published in:	Acta biomaterialia Vol. 28; pp. 64 - 75
Main Authors:	Faia-Torres, Ana B., Charnley, Mirren, Goren, Tolga, Guimond-Lischer, Stefanie, Rottmar, Markus, Maniura-Weber, Katharina, Spencer, Nicholas D., Reis, Rui L., Textor, Marcus, Neves, Nuno M.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-12-2015
Subjects:	Aged Biocompatibility Biocompatible Materials Biomaterials Biomedical materials Cell Differentiation Controllers Culture Media Differentiation High-throughput screening (gradient) Humans Mesenchymal stem cells Mesenchymal Stem Cells - cytology Microstructures Orthopedics Osteogenesis Polycaprolactone Polyesters - chemistry Programmable logic devices Surface Properties Surgical implants High-throughput screening (gradient) Microstructures Osteogenesis Biomaterials Mesenchymal stem cells
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