Long noncoding RNA Neat1 modulates myogenesis by recruiting Ezh2

Neat1 is widely expressed in many tissues and cells and exerts pro-proliferation effects on many cancer cells. However, little is known about the function of Neat1 in myogenesis. Here we characterized the roles of Neat1 in muscle cell formation and muscle regeneration. Gain- or loss-of-function stud...

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Bibliographic Details
Published in:	Cell death & disease Vol. 10; no. 7; pp. 505 - 15
Main Authors:	Wang, Shanshan, Zuo, Hao, Jin, Jianjun, Lv, Wei, Xu, Zaiyan, Fan, Yonghui, Zhang, Jiali, Zuo, Bo
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 26-06-2019 Springer Nature B.V
Subjects:	13/109 13/31 13/89 14/19 14/34 38/71 38/77 38/89 42/109 42/34 631/337/176/2016 631/337/384/2568 64/60 82/1 82/29 82/80 82/83 Animals Antibodies Biochemistry Biomedical and Life Sciences Blotting, Western Cell Biology Cell Culture Cell Differentiation - genetics Cell Differentiation - physiology Cell Line Cell proliferation Cell Proliferation - genetics Cell Proliferation - physiology Chromatin Immunoprecipitation Cyclin-dependent kinase Cyclin-dependent kinase inhibitor p21 Cyclin-dependent kinases Enhancer of Zeste Homolog 2 Protein - genetics Enhancer of Zeste Homolog 2 Protein - metabolism Enzyme inhibitors Fluorescent Antibody Technique Immunology Kinases Life Sciences Male Mice Mice, Inbred C57BL Muscle Development - genetics Muscle Development - physiology Muscle Fibers, Skeletal - cytology Muscle Fibers, Skeletal - metabolism Myoblasts - cytology Myoblasts - metabolism Myogenesis Myogenin - genetics Myogenin - metabolism Promoter Regions, Genetic - genetics Real-Time Polymerase Chain Reaction Ribonucleic acid RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Transcription
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