Primary treatment of pelvic organ prolapse: pessary use versus prolapse surgery
Introduction and hypothesis The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP). Methods This was a prospective cohort study performed in a Dutch teaching hospital in women with sy...
Saved in:
| Published in: | International Urogynecology Journal Vol. 29; no. 1; pp. 99 - 107 |
|---|---|
| Main Authors: | , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
London
Springer London
01-01-2018
Springer Nature B.V |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Introduction and hypothesis
The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP).
Methods
This was a prospective cohort study performed in a Dutch teaching hospital in women with symptomatic POP of stage II or higher requiring treatment. Patients were treated according to their preference with a pessary or prolapse surgery. The primary endpoint was disease-specific quality of life at 12 months follow-up according to the prolapse domain of the Urogenital Distress Inventory (UDI) questionnaire. Secondary outcomes included adverse events and additional interventions. To show a difference of ten points in the primary outcome, we needed to randomize 80 women (power 80%, α 0.05, taking 10% attrition into account).
Results
We included 113 women (74 in the pessary group, 39 in the surgery group). After 12 months, the median prolapse domain score was 0 (10th to 90th percentile 0–33) in the pessary group and 0 (10th to 90th percentile 0–0) in the surgery group (
p
< 0.01). Differences in other domain scores were not statistically significant. In the pessary group, 28% (21/74) of the women had a surgical intervention versus 3% (1/39) reoperations in the surgery group (
p
= 0.01).
Conclusions
In women with POP of stage II or higher undergoing surgery, prolapse symptoms were less severe than in those who were treated with a pessary, but 72% of women who were treated with a pessary did not opt for surgery.
Trial registration number:
Dutch trial register NTR2856. |
|---|---|
| AbstractList | Introduction and hypothesis
The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP).
Methods
This was a prospective cohort study performed in a Dutch teaching hospital in women with symptomatic POP of stage II or higher requiring treatment. Patients were treated according to their preference with a pessary or prolapse surgery. The primary endpoint was disease-specific quality of life at 12 months follow-up according to the prolapse domain of the Urogenital Distress Inventory (UDI) questionnaire. Secondary outcomes included adverse events and additional interventions. To show a difference of ten points in the primary outcome, we needed to randomize 80 women (power 80%, α 0.05, taking 10% attrition into account).
Results
We included 113 women (74 in the pessary group, 39 in the surgery group). After 12 months, the median prolapse domain score was 0 (10th to 90th percentile 0–33) in the pessary group and 0 (10th to 90th percentile 0–0) in the surgery group (
p
< 0.01). Differences in other domain scores were not statistically significant. In the pessary group, 28% (21/74) of the women had a surgical intervention versus 3% (1/39) reoperations in the surgery group (
p
= 0.01).
Conclusions
In women with POP of stage II or higher undergoing surgery, prolapse symptoms were less severe than in those who were treated with a pessary, but 72% of women who were treated with a pessary did not opt for surgery.
Trial registration number:
Dutch trial register NTR2856. INTRODUCTION AND HYPOTHESISThe objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP).METHODSThis was a prospective cohort study performed in a Dutch teaching hospital in women with symptomatic POP of stage II or higher requiring treatment. Patients were treated according to their preference with a pessary or prolapse surgery. The primary endpoint was disease-specific quality of life at 12 months follow-up according to the prolapse domain of the Urogenital Distress Inventory (UDI) questionnaire. Secondary outcomes included adverse events and additional interventions. To show a difference of ten points in the primary outcome, we needed to randomize 80 women (power 80%, α 0.05, taking 10% attrition into account).RESULTSWe included 113 women (74 in the pessary group, 39 in the surgery group). After 12 months, the median prolapse domain score was 0 (10th to 90th percentile 0-33) in the pessary group and 0 (10th to 90th percentile 0-0) in the surgery group (p < 0.01). Differences in other domain scores were not statistically significant. In the pessary group, 28% (21/74) of the women had a surgical intervention versus 3% (1/39) reoperations in the surgery group (p = 0.01).CONCLUSIONSIn women with POP of stage II or higher undergoing surgery, prolapse symptoms were less severe than in those who were treated with a pessary, but 72% of women who were treated with a pessary did not opt for surgery.TRIAL REGISTRATION NUMBERDutch trial register NTR2856. Introduction and hypothesisThe objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP).MethodsThis was a prospective cohort study performed in a Dutch teaching hospital in women with symptomatic POP of stage II or higher requiring treatment. Patients were treated according to their preference with a pessary or prolapse surgery. The primary endpoint was disease-specific quality of life at 12 months follow-up according to the prolapse domain of the Urogenital Distress Inventory (UDI) questionnaire. Secondary outcomes included adverse events and additional interventions. To show a difference of ten points in the primary outcome, we needed to randomize 80 women (power 80%, α 0.05, taking 10% attrition into account).ResultsWe included 113 women (74 in the pessary group, 39 in the surgery group). After 12 months, the median prolapse domain score was 0 (10th to 90th percentile 0–33) in the pessary group and 0 (10th to 90th percentile 0–0) in the surgery group (p < 0.01). Differences in other domain scores were not statistically significant. In the pessary group, 28% (21/74) of the women had a surgical intervention versus 3% (1/39) reoperations in the surgery group (p = 0.01).ConclusionsIn women with POP of stage II or higher undergoing surgery, prolapse symptoms were less severe than in those who were treated with a pessary, but 72% of women who were treated with a pessary did not opt for surgery.Trial registration number: Dutch trial register NTR2856. The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ prolapse (POP). This was a prospective cohort study performed in a Dutch teaching hospital in women with symptomatic POP of stage II or higher requiring treatment. Patients were treated according to their preference with a pessary or prolapse surgery. The primary endpoint was disease-specific quality of life at 12 months follow-up according to the prolapse domain of the Urogenital Distress Inventory (UDI) questionnaire. Secondary outcomes included adverse events and additional interventions. To show a difference of ten points in the primary outcome, we needed to randomize 80 women (power 80%, α 0.05, taking 10% attrition into account). We included 113 women (74 in the pessary group, 39 in the surgery group). After 12 months, the median prolapse domain score was 0 (10th to 90th percentile 0-33) in the pessary group and 0 (10th to 90th percentile 0-0) in the surgery group (p < 0.01). Differences in other domain scores were not statistically significant. In the pessary group, 28% (21/74) of the women had a surgical intervention versus 3% (1/39) reoperations in the surgery group (p = 0.01). In women with POP of stage II or higher undergoing surgery, prolapse symptoms were less severe than in those who were treated with a pessary, but 72% of women who were treated with a pessary did not opt for surgery. Dutch trial register NTR2856. |
| Author | Troost, Stephanie Bongers, Marlies Y. Mol, Ben Willem J. Coolen, Anne-Lotte W. M. Roovers, Jan- Paul W. R. |
| Author_xml | – sequence: 1 givenname: Anne-Lotte W. M. orcidid: 0000-0002-0056-0804 surname: Coolen fullname: Coolen, Anne-Lotte W. M. email: anne_lotte_coolen@hotmail.com organization: Department of Gynecology and Obstetics, Máxima Medical Centre – sequence: 2 givenname: Stephanie surname: Troost fullname: Troost, Stephanie organization: Department of Gynecology and Obstetics, Máxima Medical Centre – sequence: 3 givenname: Ben Willem J. surname: Mol fullname: Mol, Ben Willem J. organization: Department of Gynaecology and Obstetrics, The Robinson Research Institute, School of Paediatrics and Reproductive Health, University of Adelaide – sequence: 4 givenname: Jan- Paul W. R. surname: Roovers fullname: Roovers, Jan- Paul W. R. organization: Department of Gynaecology and Obstetrics, Academic Medical Centre Amsterdam – sequence: 5 givenname: Marlies Y. surname: Bongers fullname: Bongers, Marlies Y. organization: Department of Gynecology and Obstetics, Máxima Medical Centre, Department of Gynaecology and Obstetrics, Grow School of Oncology and Biological Diversity, Maastricht University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28600758$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kU9r3DAQxUVJaDZpP0AvxdBLL25GkvXHPRRCaJNCIDm0Z6GVx1sHr-Vq7CX59tXidEkLOQ3o_eZpZt4pOxrigIy94_CJA5hzAuC1KIGbUkojyodXbMUrKUsJQh6xFdQyK5UWJ-yU6B4AKlDwmp0Iq3O_sit2e5e6rU-PxZTQT1scpiK2xYj9rgtFTBs_FGOKvR8JP-dnoj07ExY7TDTTQSxoThtMj2_Ycet7wrdP9Yz9_Pb1x-V1eXN79f3y4qYMSuqpFMryeq1lY9pmDbW2AnJBLb0PXIrG1K2RvlWhWaMWolbccosaGx-E4UHIM_Zl8R3n9RabkAdPvnfjso2LvnP_KkP3y23izimjqgogG3x8Mkjx94w0uW1HAfveDxhncrwGWwlra5XRD_-h93FOQ14vU7bSxi6GfKFCikQJ28MwHNw-LrfE5XJcbh-Xe8g9759vcej4m08GxAJQloZ84Gdfv-j6B4VLo9w |
| CitedBy_id | crossref_primary_10_1002_14651858_CD004010_pub4 crossref_primary_10_1097_SPV_0000000000001279 crossref_primary_10_1177_17455057231181012 crossref_primary_10_3390_jcm9113773 crossref_primary_10_1097_GME_0000000000001751 crossref_primary_10_1007_s00192_020_04338_w crossref_primary_10_1007_s00192_020_04314_4 crossref_primary_10_2147_IJWH_S406048 crossref_primary_10_4240_wjgs_v13_i9_1063 crossref_primary_10_1007_s00192_023_05627_w crossref_primary_10_1097_GME_0000000000001939 crossref_primary_10_1007_s00192_021_04843_6 crossref_primary_10_2147_IJWH_S413670 crossref_primary_10_1016_j_gine_2020_04_002 crossref_primary_10_1177_2053369120937594 crossref_primary_10_3390_medicina60040547 crossref_primary_10_1097_GME_0000000000001633 crossref_primary_10_1016_j_cont_2024_101318 crossref_primary_10_1097_SPV_0000000000001293 crossref_primary_10_1007_s00404_023_07177_4 crossref_primary_10_1001_jama_2022_22385 crossref_primary_10_1007_s11884_018_0469_0 crossref_primary_10_1186_s12905_019_0749_7 crossref_primary_10_1002_nau_24477 crossref_primary_10_1111_luts_12411 crossref_primary_10_1016_j_gofs_2018_05_003 crossref_primary_10_1098_rsfs_2019_0014 crossref_primary_10_1080_15398285_2020_1810966 crossref_primary_10_1007_s00192_019_03919_8 crossref_primary_10_1016_j_ajog_2023_01_006 crossref_primary_10_3889_oamjms_2022_8804 crossref_primary_10_1002_nau_24458 crossref_primary_10_1007_s00404_019_05046_7 crossref_primary_10_1097_SPV_0000000000000731 crossref_primary_10_1007_s00192_021_04817_8 crossref_primary_10_1111_1471_0528_16950 crossref_primary_10_1097_GME_0000000000001849 crossref_primary_10_4111_icu_20210395 crossref_primary_10_1097_LGT_0000000000000629 |
| Cites_doi | 10.1097/AOG.0b013e3181d055d4 10.1002/nau.10038 10.1097/01.AOG.0000222903.38684.cc 10.1159/000336634 10.1007/s00192-011-1390-7 10.1016/j.ogc.2009.08.010 10.1111/j.1471-0528.2005.00568.x 10.1056/NEJMoa1111967 10.1111/j.1471-0528.2009.02380.x 10.1007/s00192-010-1340-9 10.1111/j.1471-0528.2004.00001.x 10.1016/j.ajog.2003.10.711 10.1007/s00192-004-1226-9 10.1016/S0002-9378(96)70243-0 10.1007/s00192-009-0902-1 10.1016/S0029-7844(97)00058-6 10.1016/j.ajog.2007.08.013 10.1016/j.fertnstert.2008.02.142 10.1007/s00192-015-2686-9 10.1007/s10350-007-9147-6 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2017 International Urogynecology Journal is a copyright of Springer, (2017). All Rights Reserved. |
| Copyright_xml | – notice: The Author(s) 2017 – notice: International Urogynecology Journal is a copyright of Springer, (2017). All Rights Reserved. |
| DBID | C6C NPM AAYXX CITATION 3V. 7X7 7XB 88E 8AO 8FI 8FJ 8FK ABUWG AFKRA BENPR CCPQU FYUFA GHDGH K9. M0S M1P PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| DOI | 10.1007/s00192-017-3372-x |
| DatabaseName | SpringerOpen (Open Access) PubMed CrossRef ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Databases ProQuest One Community College Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) Medical Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | PubMed CrossRef ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Pharma Collection ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central ProQuest Health & Medical Complete Health Research Premium Collection ProQuest Medical Library ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) ProQuest One Academic ProQuest Medical Library (Alumni) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic ProQuest One Academic Eastern Edition PubMed |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1433-3023 |
| EndPage | 107 |
| ExternalDocumentID | 10_1007_s00192_017_3372_x 28600758 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: Maastricht University – fundername: ; |
| GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C .86 .VR 06C 06D 0R~ 0VY 1N0 1SB 2.D 203 28- 29J 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5VS 67Z 6NX 7X7 88E 8AO 8FI 8FJ 8UJ 95- 95. 95~ 96X AAAVM AABHQ AABYN AAFGU AAHNG AAIAL AAJKR AAKSU AANXM AANZL AAPBV AARHV AARTL AATNV AATVU AAUYE AAWCG AAYFA AAYIU AAYQN AAYTO ABBBX ABBXA ABDZT ABECU ABFGW ABFTV ABHLI ABHQN ABIPD ABJNI ABJOX ABKAS ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABPTK ABQBU ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACBMV ACBRV ACBXY ACBYP ACGFS ACHSB ACHXU ACIGE ACIPQ ACKNC ACMDZ ACMLO ACOKC ACOMO ACSNA ACTTH ACUDM ACVWB ACWMK ADBBV ADHHG ADHIR ADIMF ADINQ ADJJI ADKNI ADKPE ADMDM ADOXG ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEEQQ AEFIE AEFTE AEGAL AEGNC AEJHL AEJRE AEKMD AENEX AEOHA AEPYU AESKC AESTI AETLH AEVLU AEVTX AEXYK AFAFS AFEXP AFKRA AFLOW AFNRJ AFQWF AFWTZ AFZKB AGAYW AGDGC AGGBP AGGDS AGJBK AGKHE AGMZJ AGQMX AGWIL AGWZB AGYKE AHAVH AHBYD AHIZS AHKAY AHMBA AHSBF AHYZX AIAKS AIIXL AILAN AIMYW AITGF AJBLW AJDOV AJRNO AJZVZ AKMHD AKQUC ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BVXVI C6C CCPQU CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 EBD EBLON EBS EIOEI EJD EMOBN EN4 ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GRRUI GXS HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ IMOTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH LAS LLZTM M1P M4Y MA- N2Q N9A NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R4E R89 R9I RHV RIG RNI ROL RPX RSV RZK S16 S1Z S26 S27 S28 S37 S3B SAP SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UNUBA UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK8 YLTOR Z45 Z7U Z7W Z81 Z82 Z87 Z8O Z8Q Z8U Z8V Z91 ZMTXR ZOVNA ~EX AACDK AAEOY AAJBT AASML AAYZH ABAKF ACAOD ACDTI ACZOJ AEFQL AEMSY AFBBN AGQEE AGRTI AIGIU AJOOF ALIPV H13 NPM AAYXX CITATION 7XB 8FK K9. PQEST PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c536t-25819b63d7fdb096820b09e63aac132d79f73af5cdbe622951818e6edac271c23 |
| IEDL.DBID | AEJHL |
| ISSN | 0937-3462 |
| IngestDate | Tue Sep 17 21:18:57 EDT 2024 Fri Oct 25 10:29:34 EDT 2024 Mon Nov 04 11:12:46 EST 2024 Thu Nov 21 23:35:12 EST 2024 Wed Oct 16 00:59:36 EDT 2024 Sat Dec 16 12:06:01 EST 2023 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Pessary Prolapse surgery Pelvic organ prolapse |
| Language | English |
| License | Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c536t-25819b63d7fdb096820b09e63aac132d79f73af5cdbe622951818e6edac271c23 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| ORCID | 0000-0002-0056-0804 |
| OpenAccessLink | http://link.springer.com/10.1007/s00192-017-3372-x |
| PMID | 28600758 |
| PQID | 1984678400 |
| PQPubID | 326303 |
| PageCount | 9 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_5754400 proquest_miscellaneous_1908428895 proquest_journals_1984678400 crossref_primary_10_1007_s00192_017_3372_x pubmed_primary_28600758 springer_journals_10_1007_s00192_017_3372_x |
| PublicationCentury | 2000 |
| PublicationDate | 2018-01-01 |
| PublicationDateYYYYMMDD | 2018-01-01 |
| PublicationDate_xml | – month: 01 year: 2018 text: 2018-01-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England – name: Guildford |
| PublicationSubtitle | Including Pelvic Floor Dysfunction |
| PublicationTitle | International Urogynecology Journal |
| PublicationTitleAbbrev | Int Urogynecol J |
| PublicationTitleAlternate | Int Urogynecol J |
| PublicationYear | 2018 |
| Publisher | Springer London Springer Nature B.V |
| Publisher_xml | – name: Springer London – name: Springer Nature B.V |
| References | Lone, Thakar, Sultan (CR14) 2015; 26 Kuhn, Bapst, Stadlmayr, Vits, Mueller (CR9) 2009; 5 Bump, Mattiasson, Bø, Brubaker, DeLancey, Klarskov (CR15) 1996; 175 Olsen, Smith, Bergstrom, Colling, Clark (CR2) 1997; 89 Broens-Oostveen, Mom, Lagro-Janssen (CR12) 2004; 148 Clemons, Aguilar, Tillinghast, Jackson, Myers (CR20) 2004; 190 Van der Vaart, de Leeuw, Roovers, Heintz (CR16) 2003; 22 Richter, Burgio, Brubaker, Nygaard, Ye, Weidner (CR3) 2010; 115 Digesu, Chaliha, Salvatore, Hutchings, Khullar (CR6) 2005; 112 Komesu, Rogers, Rode, Craig, Gallegos, Montoya, Swartz (CR8) 2007; 197 Atnip (CR4) 2009; 36 Abdool, Thakar, Sultan, Oliver (CR11) 2011; 22 Wei, Nygaard, Richter, Nager, Barber (CR19) 2012; 366 Thys, Roovers, Geomini, Bongers (CR5) 2012; 74 Bai, Yoon, Kwon, Shin, Kim, Park (CR21) 2005; 16 Roovers, van der Bom, van der Vaart (CR17) 2008; 51 Slieker-ten Hove, Pool-Goudzwaard, Eijkemans, Steegers-Theunissen, Burger, Vierhout (CR1) 2009; 20 Lamers, Broekman, Milani (CR10) 2011; 22 Roovers, van der Vaart, van der Bom, Heintz (CR18) 2004; 111 Fernando, Thakar, Sultan, Shah, Jones (CR7) 2006; 108 Sarma, Ying, Moore (CR13) 2009; 116 21161179 - Int Urogynecol J. 2011 Mar;22(3):273-8 22716974 - N Engl J Med. 2012 Jun 21;366(25):2358-67 21472447 - Int Urogynecol J. 2011 Jun;22(6):637-44 15958002 - BJOG. 2005 Jul;112(7):971-6 9083302 - Obstet Gynecol. 1997 Apr;89(4):501-6 20177294 - Obstet Gynecol. 2010 Mar;115(3):609-17 19906018 - BJOG. 2009 Dec;116(13):1715-21 8694033 - Am J Obstet Gynecol. 1996 Jul;175(1):10-7 18443878 - Dis Colon Rectum. 2008 Jul;51(7):1068-72; discussion 1072-3 18410935 - Fertil Steril. 2009 May;91(5):1914-8 14687052 - BJOG. 2004 Jan;111(1):50-6 16816061 - Obstet Gynecol. 2006 Jul;108(1):93-9 15326649 - Ned Tijdschr Geneeskd. 2004 Jul 17;148(29):1444-8 19932415 - Obstet Gynecol Clin North Am. 2009 Sep;36(3):541-63 18060953 - Am J Obstet Gynecol. 2007 Dec;197(6):620.e1-6 19444368 - Int Urogynecol J Pelvic Floor Dysfunct. 2009 Sep;20(9):1037-45 25862241 - Int Urogynecol J. 2015 Sep;26(9):1305-12 15578156 - Int Urogynecol J Pelvic Floor Dysfunct. 2005 May-Jun;16(3):182-6; discussion 186 12579625 - Neurourol Urodyn. 2003;22(2):97-104 15118635 - Am J Obstet Gynecol. 2004 Apr;190(4):1025-9 22759810 - Gynecol Obstet Invest. 2012;74(1):6-12 Z Abdool (3372_CR11) 2011; 22 SD Thys (3372_CR5) 2012; 74 JP Roovers (3372_CR17) 2008; 51 BH Lamers (3372_CR10) 2011; 22 A Kuhn (3372_CR9) 2009; 5 JP Roovers (3372_CR18) 2004; 111 AL Olsen (3372_CR2) 1997; 89 JL Clemons (3372_CR20) 2004; 190 HE Richter (3372_CR3) 2010; 115 RJ Fernando (3372_CR7) 2006; 108 RC Bump (3372_CR15) 1996; 175 SD Atnip (3372_CR4) 2009; 36 F Lone (3372_CR14) 2015; 26 SW Bai (3372_CR21) 2005; 16 MC Broens-Oostveen (3372_CR12) 2004; 148 CH Van der Vaart (3372_CR16) 2003; 22 GA Digesu (3372_CR6) 2005; 112 S Sarma (3372_CR13) 2009; 116 MC Slieker-ten Hove (3372_CR1) 2009; 20 JT Wei (3372_CR19) 2012; 366 YM Komesu (3372_CR8) 2007; 197 |
| References_xml | – volume: 115 start-page: 609 issue: 3 year: 2010 end-page: 617 ident: CR3 article-title: Continence pessary compared with behavioral therapy or combined therapy for stress incontinence: a randomized controlled trial publication-title: Obstet Gynecol doi: 10.1097/AOG.0b013e3181d055d4 contributor: fullname: Weidner – volume: 148 start-page: 1444 issue: 29 year: 2004 end-page: 1448 ident: CR12 article-title: Genital prolapse; treatment and course in four general practices publication-title: Ned Tijdschr Geneeskd contributor: fullname: Lagro-Janssen – volume: 22 start-page: 97 issue: 2 year: 2003 end-page: 104 ident: CR16 article-title: Measuring health-related quality of life in women with urogenital dysfunction: the Urogenital Distress Inventory and Incontinence Impact Questionnaire revisited publication-title: Neurourol Urodyn doi: 10.1002/nau.10038 contributor: fullname: Heintz – volume: 108 start-page: 93 issue: 1 year: 2006 end-page: 99 ident: CR7 article-title: Effect of vaginal pessaries on symptoms associated with pelvic organ prolapse publication-title: Obstet Gynecol doi: 10.1097/01.AOG.0000222903.38684.cc contributor: fullname: Jones – volume: 74 start-page: 6 year: 2012 end-page: 12 ident: CR5 article-title: Do patients prefer a pessary or surgery as primary treatment for pelvic organ prolapse publication-title: Gynecol Obstet Invest doi: 10.1159/000336634 contributor: fullname: Bongers – volume: 22 start-page: 637 year: 2011 end-page: 664 ident: CR10 article-title: Pessary treatment for pelvic organ prolapse and health-related quality of life: a review publication-title: Int Urogynecol J doi: 10.1007/s00192-011-1390-7 contributor: fullname: Milani – volume: 36 start-page: 541 issue: 3 year: 2009 end-page: 563 ident: CR4 article-title: Pessary use and management for pelvic organ prolapse publication-title: Obstet Gynecol Clin North Am doi: 10.1016/j.ogc.2009.08.010 contributor: fullname: Atnip – volume: 112 start-page: 971 year: 2005 end-page: 976 ident: CR6 article-title: The relationship of vaginal prolapse severity to symptoms and quality of life publication-title: BJOG doi: 10.1111/j.1471-0528.2005.00568.x contributor: fullname: Khullar – volume: 366 start-page: 2358 year: 2012 end-page: 2367 ident: CR19 article-title: A midurethral sling to reduce incontinence after vaginal prolapse repair publication-title: N Engl J Med doi: 10.1056/NEJMoa1111967 contributor: fullname: Barber – volume: 116 start-page: 1715 issue: 13 year: 2009 end-page: 1721 ident: CR13 article-title: Long-term vaginal ring pessary use: discontinuation rates and adverse events publication-title: BJOG doi: 10.1111/j.1471-0528.2009.02380.x contributor: fullname: Moore – volume: 22 start-page: 273 year: 2011 end-page: 278 ident: CR11 article-title: Prospective evaluation of outcome of vaginal pessaries versus surgery in women with symptomatic pelvic organ prolapse publication-title: Int Urogynecol J doi: 10.1007/s00192-010-1340-9 contributor: fullname: Oliver – volume: 111 start-page: 50 year: 2004 end-page: 56 ident: CR18 article-title: A randomised controlled trial comparing abdominal and vaginal prolapse surgery: effects on urogenital function publication-title: Br J Obstet Gynaecol doi: 10.1111/j.1471-0528.2004.00001.x contributor: fullname: Heintz – volume: 190 start-page: 1025 issue: 4 year: 2004 end-page: 1029 ident: CR20 article-title: Patient satisfaction and changes in prolapse and urinary symptoms in women who were fitted successfully with a pessary for pelvic organ prolapse publication-title: Am J Obstet Gynecol doi: 10.1016/j.ajog.2003.10.711 contributor: fullname: Myers – volume: 16 start-page: 182 issue: 3 year: 2005 end-page: 186 ident: CR21 article-title: Survey of the characteristics and satisfaction degree of the patients using a pessary publication-title: Int Urogynecol J Pelvic Floor Dysfunct doi: 10.1007/s00192-004-1226-9 contributor: fullname: Park – volume: 175 start-page: 10 issue: 1 year: 1996 end-page: 17 ident: CR15 article-title: The standardization of terminology of female pelvic organ prolapse and pelvic floor dysfunction publication-title: Am J Obstet Gynecol doi: 10.1016/S0002-9378(96)70243-0 contributor: fullname: Klarskov – volume: 20 start-page: 1037 year: 2009 end-page: 1045 ident: CR1 article-title: The prevalence of pelvic organ prolapse symptoms and signs and their relation with bladder and bowel disorders in a general female population publication-title: Int Urogynecol J Pelvic Floor Dysfunct doi: 10.1007/s00192-009-0902-1 contributor: fullname: Vierhout – volume: 89 start-page: 501 issue: 4 year: 1997 end-page: 506 ident: CR2 article-title: Epidemiology of surgically managed pelvic organ and urinary incontinence publication-title: Obstet Gynecol doi: 10.1016/S0029-7844(97)00058-6 contributor: fullname: Clark – volume: 197 start-page: 620.e1 year: 2007 end-page: 620.e6 ident: CR8 article-title: Pelvic floor symptom changes in pessary users publication-title: Am J Obstet Gynecol doi: 10.1016/j.ajog.2007.08.013 contributor: fullname: Swartz – volume: 5 start-page: 1914 year: 2009 end-page: 1918 ident: CR9 article-title: Sexual and organ function in patients with symptomatic prolapse: are pessaries helpful? publication-title: Fertil Steril doi: 10.1016/j.fertnstert.2008.02.142 contributor: fullname: Mueller – volume: 26 start-page: 1305 year: 2015 end-page: 1312 ident: CR14 article-title: One-year prospective comparison of vaginal pessaries and surgery for pelvic organ prolapse using the validated ICIQ-VS and ICIQ-UI (SF) questionnaires publication-title: Int Urogynecol J doi: 10.1007/s00192-015-2686-9 contributor: fullname: Sultan – volume: 51 start-page: 1068 issue: 7 year: 2008 end-page: 1072 ident: CR17 article-title: Hysterectomy does not cause constipation publication-title: Dis Colon Rectum doi: 10.1007/s10350-007-9147-6 contributor: fullname: van der Vaart – volume: 89 start-page: 501 issue: 4 year: 1997 ident: 3372_CR2 publication-title: Obstet Gynecol doi: 10.1016/S0029-7844(97)00058-6 contributor: fullname: AL Olsen – volume: 20 start-page: 1037 year: 2009 ident: 3372_CR1 publication-title: Int Urogynecol J Pelvic Floor Dysfunct doi: 10.1007/s00192-009-0902-1 contributor: fullname: MC Slieker-ten Hove – volume: 116 start-page: 1715 issue: 13 year: 2009 ident: 3372_CR13 publication-title: BJOG doi: 10.1111/j.1471-0528.2009.02380.x contributor: fullname: S Sarma – volume: 190 start-page: 1025 issue: 4 year: 2004 ident: 3372_CR20 publication-title: Am J Obstet Gynecol doi: 10.1016/j.ajog.2003.10.711 contributor: fullname: JL Clemons – volume: 197 start-page: 620.e1 year: 2007 ident: 3372_CR8 publication-title: Am J Obstet Gynecol doi: 10.1016/j.ajog.2007.08.013 contributor: fullname: YM Komesu – volume: 5 start-page: 1914 year: 2009 ident: 3372_CR9 publication-title: Fertil Steril doi: 10.1016/j.fertnstert.2008.02.142 contributor: fullname: A Kuhn – volume: 112 start-page: 971 year: 2005 ident: 3372_CR6 publication-title: BJOG doi: 10.1111/j.1471-0528.2005.00568.x contributor: fullname: GA Digesu – volume: 111 start-page: 50 year: 2004 ident: 3372_CR18 publication-title: Br J Obstet Gynaecol doi: 10.1111/j.1471-0528.2004.00001.x contributor: fullname: JP Roovers – volume: 108 start-page: 93 issue: 1 year: 2006 ident: 3372_CR7 publication-title: Obstet Gynecol doi: 10.1097/01.AOG.0000222903.38684.cc contributor: fullname: RJ Fernando – volume: 366 start-page: 2358 year: 2012 ident: 3372_CR19 publication-title: N Engl J Med doi: 10.1056/NEJMoa1111967 contributor: fullname: JT Wei – volume: 115 start-page: 609 issue: 3 year: 2010 ident: 3372_CR3 publication-title: Obstet Gynecol doi: 10.1097/AOG.0b013e3181d055d4 contributor: fullname: HE Richter – volume: 22 start-page: 637 year: 2011 ident: 3372_CR10 publication-title: Int Urogynecol J doi: 10.1007/s00192-011-1390-7 contributor: fullname: BH Lamers – volume: 74 start-page: 6 year: 2012 ident: 3372_CR5 publication-title: Gynecol Obstet Invest doi: 10.1159/000336634 contributor: fullname: SD Thys – volume: 22 start-page: 97 issue: 2 year: 2003 ident: 3372_CR16 publication-title: Neurourol Urodyn doi: 10.1002/nau.10038 contributor: fullname: CH Van der Vaart – volume: 175 start-page: 10 issue: 1 year: 1996 ident: 3372_CR15 publication-title: Am J Obstet Gynecol doi: 10.1016/S0002-9378(96)70243-0 contributor: fullname: RC Bump – volume: 51 start-page: 1068 issue: 7 year: 2008 ident: 3372_CR17 publication-title: Dis Colon Rectum doi: 10.1007/s10350-007-9147-6 contributor: fullname: JP Roovers – volume: 148 start-page: 1444 issue: 29 year: 2004 ident: 3372_CR12 publication-title: Ned Tijdschr Geneeskd contributor: fullname: MC Broens-Oostveen – volume: 22 start-page: 273 year: 2011 ident: 3372_CR11 publication-title: Int Urogynecol J doi: 10.1007/s00192-010-1340-9 contributor: fullname: Z Abdool – volume: 16 start-page: 182 issue: 3 year: 2005 ident: 3372_CR21 publication-title: Int Urogynecol J Pelvic Floor Dysfunct doi: 10.1007/s00192-004-1226-9 contributor: fullname: SW Bai – volume: 36 start-page: 541 issue: 3 year: 2009 ident: 3372_CR4 publication-title: Obstet Gynecol Clin North Am doi: 10.1016/j.ogc.2009.08.010 contributor: fullname: SD Atnip – volume: 26 start-page: 1305 year: 2015 ident: 3372_CR14 publication-title: Int Urogynecol J doi: 10.1007/s00192-015-2686-9 contributor: fullname: F Lone |
| SSID | ssj0004050 ssj0001127576 |
| Score | 2.4410775 |
| Snippet | Introduction and hypothesis
The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary... The objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary treatments for pelvic organ... Introduction and hypothesisThe objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary... INTRODUCTION AND HYPOTHESISThe objective of this study was to compare the functional outcomes after pessary treatment and after prolapse surgery as primary... |
| SourceID | pubmedcentral proquest crossref pubmed springer |
| SourceType | Open Access Repository Aggregation Database Index Database Publisher |
| StartPage | 99 |
| SubjectTerms | Gynecology Health risk assessment Medicine Medicine & Public Health Original Original Article Pelvic organ prolapse Surgery Urology |
| Title | Primary treatment of pelvic organ prolapse: pessary use versus prolapse surgery |
| URI | https://link.springer.com/article/10.1007/s00192-017-3372-x https://www.ncbi.nlm.nih.gov/pubmed/28600758 https://www.proquest.com/docview/1984678400 https://search.proquest.com/docview/1908428895 https://pubmed.ncbi.nlm.nih.gov/PMC5754400 |
| Volume | 29 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB7BVkJcWl6FtAUZqSeQq6ydxE5vK9hqhehDKkjcItsZq4gqu2oaqT-_47xgWTjAKVI8TmyP7flmxp4BOMTc5yZPLJ8653lipeDW25w7iz4VpZvGGAxui0t19k1_nIcwOWI0XVQ_jgaPZLtRj3fdWjDCw6YqpRKccOMWiZ40mcDWbP5p8fmnZSXELA9CdrgdGbd5Wkl1p6pJJgbf5p8-ui6dNiDn5snJ39ynrVQ62fmf_jyB7R6Dslk3aZ7CA6yewaPT3sv-HM4vuhAUbDyFzpaerfCadhXWpoFi1OZrs6rxmF7XdaBtamThiEdTj4Ws7u5cv4CvJ_MvHxa8T7zAXSqzWy5Swgk2k6XypSUdh1ACPTCTxjjSXkuVeyWNT11pMQv5wAkmaMywNE6oqRNyFybVssJXwKg-qaDKEjAziUyUcd7EqHOtDRJSwwjeDQNerLrOFWMk5XaIChqiIgxRcRfBwcCSol9qdTHNA4QiPTWO4O1YTIskeD5Mhcsm0MSa9CydpxG87Dg4_k3oEKI_1RGoNd6OBCEA93pJ9f2qDcSdhuiB4b_vBxb_0qy_dWLvn6j34TFBNN0ZfQ5gcnvT4Gt4WJfNm37e3wNcuf4V |
| link.rule.ids | 230,315,782,786,887,27934,27935,41074,42143,48345,48348,48358,49650,49653,49663,52154 |
| linkProvider | Springer Nature |
| linkToHtml | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB7BVgIulGcJFDASJ5ClbJzEDreqdNmKtiCxSNwi2xmLSlV2RRqJn89MXrAUDnCKFI_jx8T2Nx77G4CXWITCFqmTc--DTJ1KpAuukN5hyJLKz2PkDbflJ332xbw9YpocNd6F6U67jy7JbqaeLrt1aETyrKqUTiQBxx0mO49nsHNwvHq3-Lm1wqTlvMqO1yPjLlAr2e6UNc2T0bn5p49uL09XMOfVo5O_-U-7ZWmx-18NugO3BxQqDvrf5i5cw_oe3Dgd_Oz34cPHnoRCTOfQxTqIDV7QvCK6QFCCKn1hNw2-oddNw7Jtg4IPebTNlCia_tb1A_i8OFodLuUQekH6TOWXMskIKbhcVTpUjqwcwgn0wFxZ68l-rXQRtLIh85XDnCOCE1AwmGNlfaLnPlEPYVava3wEgvKTEaodQTObqlRbH2yMpjDGImE1jODV2OPlpm9cOXEpd11UUheV3EXl9wj2R52Uw2BrynnBIIos1TiCF1MyDRP2fdga1y3LxIYsLVNkEez1KpxKSwyT9GcmAr2l3EmAKbi3U-rzrx0Vd8b8gVzu61HFv1Trb414_E_Sz-HmcnV6Up4cn71_ArcIsJl-C2gfZpffWnwK15uqfTYMgh95vgIL |
| linkToPdf | http://sdu.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3di9QwEB90Dw5f_P6onhrBJyVct2mb1Bc5vF1WPc8DFXwrSTpB4egudgv--c70S9fTB_Gp0CRtM9Mkv8nM_ALwFItQ2CJ1cu59kKlTiXTBFdI7DFlS-XmMvOG2-qBPP5vjBdPkvBxzYbpo99El2ec0MEtTvT3cVOFwSnzrkInkGVYpnUgCkXsphxbOYO9o8WZ18nObhQnMecUdUyXj7tBWsuOpaZono6PzTw_dXaou4M-LYZS_-VK7JWp57b87dx2uDuhUHPW_0w24hPVN2H83-N9vwfuznpxCTPHpYh3EBs9pvhHdAVGCOnBuNw2-oNtNw3XbBgUHf7TNVCiaPhv7NnxaLj6-WsnhSAbpM5VvZZIRgnC5qnSoHFk_hB_ogrmy1pNdW-kiaGVD5iuHOZ8UTgDCYI6V9Yme-0TdgVm9rvEeCGpPxql2BNlsqlJtfbAxmsIYi4ThMIJno_TLTd-5cuJY7kRUkohKFlH5PYKDUT_lMAibcl4wuCILNo7gyVRMw4d9IrbGdct1YkMWmCmyCO726pzelhgm789MBHpH0VMFpubeLam_fukoujPmFeT3Ph_V_ctn_a0T9_-p9mPYPztelievT98-gCuE40y_M3QAs-23Fh_C5aZqHw3j4QfjwArX |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Primary+treatment+of+pelvic+organ+prolapse%3A+pessary+use+versus+prolapse+surgery&rft.jtitle=International+Urogynecology+Journal&rft.au=Coolen%2C+Anne-Lotte+W.+M.&rft.au=Troost%2C+Stephanie&rft.au=Mol%2C+Ben+Willem+J.&rft.au=Roovers%2C+Jan-+Paul+W.+R.&rft.date=2018-01-01&rft.pub=Springer+London&rft.issn=0937-3462&rft.eissn=1433-3023&rft.volume=29&rft.issue=1&rft.spage=99&rft.epage=107&rft_id=info:doi/10.1007%2Fs00192-017-3372-x&rft.externalDocID=10_1007_s00192_017_3372_x |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0937-3462&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0937-3462&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0937-3462&client=summon |