Follicle-stimulating hormone regulation of ovarian transcripts for steroidogenesis-related proteins and cell survival, growth and differentiation factors in vitro during early secondary oocyte growth in coho salmon

• Published in: General and comparative endocrinology Vol. 171; no. 1; pp. 52 - 63
• Main Authors: Luckenbach, J. Adam, Dickey, Jon T, Swanson, Penny
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-03-2011
• Subjects: Animals; Aromatase - genetics; cell viability; culture media; Endocrinology & Metabolism; Female; Fish Proteins - genetics; Follicle Stimulating Hormone - pharmacology; Follicle-stimulating hormone; gene expression; gene expression regulation; genes; Gonadotropin; gonadotropin receptors; growth differentiation factors; Growth factor; Immunoassay; immunoassays; messenger RNA; Oncorhynchus kisutch; oocytes; Oocytes - drug effects; Oocytes - metabolism; ovarian follicles; Ovary; Ovary - drug effects; Ovary - metabolism; puberty; Puberty onset; Reverse Transcriptase Polymerase Chain Reaction; salmon; Steroidogenesis; Teleostei; testosterone; unspecific monooxygenase; gdf9; cathepsin D gene; E2; cyp11a1; clusterin 1 gene; elongation factor-1 alpha gene; Ovary; cyp17a1; insulin-like growth factor 1a receptor gene; igf1; inhbb; inhba; FSH; igf2; very low density lipoprotein receptor gene; cyp19a1a; igf1rb; ef1a; igf1ra; cytochrome P450, subfamily XIA, polypeptide 1 gene; gonadal soma-derived factor gene; insulin-like growth factor 1b receptor gene; fshr; hydroxy-5-steroid dehydrogenase, 3 beta gene; clu1; luteinizing hormone; ctsd; hsd17b3; growth differentiation factor 9 gene; lhcgr; inhibin beta B gene; cytochrome P450, family 17, subfamily A, polypeptide 1 gene; hsd17b1; apolipoprotein E gene; steroidogenic acute regulatory protein gene; Steroidogenesis; amh; Growth factor; cytochrome P450, family 19, subfamily A, polypeptide 1a gene; insulin-like growth factor 1 gene; estradiol-17β; zona pellucida protein C gene; vldlr; transforming growth factor β; lcal; insulin-like growth factor 2 gene; T; serum lectin isoform 2 gene; hydroxysteroid (17-beta) dehydrogenase 1 gene; inhibin beta A gene; anti-Mullerian hormone gene; gsdf; Follicle-stimulating hormone; testosterone; star; follicle-stimulating hormone receptor gene; hsd3b; apoe; Gonadotropin; zpc; luteinizing hormone/choriogonadotropin receptor gene; inhibin alpha gene; inha; bmp16; Puberty onset; hydroxysteroid (17-beta) dehydrogenase 3 gene; bone morphogenetic protein 16 gene; TGFβ; LH
• ISSN: 0016-6480; 1095-6840
• DOI: 10.1016/j.ygcen.2010.12.016

Research highlights ► FSH increased testosterone and estradiol production in early secondary growth ovarian follicles of coho salmon. ► FSH upregulated ovarian steroidogenesis-related protein mRNAs, star and hsd3b , while aromatase ( cyp19a1a ) mRNA was unaffected by FSH. ► FSH affected mRNA levels for the gonadotropin receptors and specific insulin-like and transforming growth factor family genes. ► Provides evidence that FSH functions in ovarian steroidogenesis and cell survival, growth and differentiation during early secondary oocyte growth in teleosts.