Solitary cutaneous focal mucinosis: A clinicopathological study of 11 cases of soft fibroma‐like cutaneous mucinous lesions

• Published in: Journal of dermatology Vol. 44; no. 3; pp. 335 - 338
• Main Authors: Kuo, Kang‐Ling, Lee, Li‐yu, Kuo, Tseng‐tong
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01-03-2017
• Subjects: Adult; Aged; cutaneous focal mucinosis; cutaneous mucinosis; Diagnosis, Differential; Female; Fibroma - pathology; Humans; Male; Middle Aged; mucin; Mucinoses - diagnosis; Mucinoses - pathology; mucinosis; Skin Diseases - diagnosis; Skin Diseases - pathology; solitary cutaneous mucinosis; Systemic diseases; cutaneous mucinosis; cutaneous focal mucinosis; mucinosis; mucin; solitary cutaneous mucinosis
• ISSN: 0385-2407; 1346-8138
• DOI: 10.1111/1346-8138.13523

Cutaneous mucinoses encompass a variety of cutaneous disorders. Cutaneous focal mucinosis (CFM) was originally described as an asymptomatic solitary lesion characterized by abundant focal cutaneous mucin deposits. However, multiple focal mucinous lesions associated with systemic diseases have also been designated as CFM. Our clinicopathological study of 11 cases of solitary lesions confirmed that CFM is a unique primary cutaneous mucinosis unrelated to mucinosis‐associated systemic diseases. We suggest calling this group of CFM lesions “solitary CFM” to distinguish them from multiple CFM associated with mucinosis associated systemic diseases. Our cases showed slight male predominance with a median age of 50 years. They occurred most often on the extremities (45%), presented as asymptomatic solitary, white to erythematous, small, soft, fibroma‐like lesions. None of the clinical impressions were of CFM. We call attention to include solitary CFM in clinical differential diagnosis of polypoid skin lesions.