Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia

Cachexia is a life-threatening disease characterized by chronic, inflammatory muscle wasting and systemic metabolic impairment. Despite its high prevalence, there are no efficacious therapies for cachexia. Mice chronically infected with the protozoan parasite Toxoplasma gondii represent a novel anim...

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Bibliographic Details

Published in:	Heliyon Vol. 9; no. 7; p. e17411
Main Authors:	Feng, Tzu-Yu, Melchor, Stephanie J., Zhao, Xiao-Yu, Ghumman, Haider, Kester, Mark, Fox, Todd E., Ewald, Sarah E.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-07-2023 Elsevier
Subjects:	Cachexia Ceramides Lipid rebound Liver atrophy Sphingolipids TCA cycle Toxoplasma gondii Toxoplasma gondii Lipid rebound TCA cycle Ceramides Liver atrophy Cachexia Sphingolipids
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