Admixture Mapping of an Allele Affecting Interleukin 6 Soluble Receptor and Interleukin 6 Levels

Circulating levels of inflammatory markers can predict cardiovascular disease risk. To identify genes influencing the levels of these markers, we genotyped 1,343 single-nucleotide polymorphisms (SNPs) in 1,184 African Americans from the Health, Aging and Body Composition (Health ABC) Study. Using ad...

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Bibliographic Details
Published in:	American journal of human genetics Vol. 80; no. 4; pp. 716 - 726
Main Authors:	Reich, David, Patterson, Nick, Ramesh, Vijaya, De Jager, Philip L., McDonald, Gavin J., Tandon, Arti, Choy, Edwin, Hu, Donglei, Tamraz, Bani, Pawlikowska, Ludmila, Wassel-Fyr, Christina, Huntsman, Scott, Waliszewska, Alicja, Rossin, Elizabeth, Li, Rongling, Garcia, Melissa, Reiner, Alexander, Ferrell, Robert, Cummings, Steve, Kwok, Pui-Yan, Harris, Tamara, Zmuda, Joseph M., Ziv, Elad
Format:	Journal Article
Language:	English
Published:	Chicago, IL Elsevier Inc 01-04-2007 University of Chicago Press American Society of Human Genetics
Subjects:	African Americans - genetics Aged Biological and medical sciences Chromosome Mapping Chromosomes, Human, Pair 1 - genetics Classical genetics, quantitative genetics, hybrids European Continental Ancestry Group - genetics Female Fundamental and applied biological sciences. Psychology Gene Frequency General aspects. Genetic counseling Genetics of eukaryotes. Biological and molecular evolution Genomics - methods Genotype Human Humans Interleukin-6 - blood Lod Score Male Medical genetics Medical sciences Molecular and cellular biology Polymorphism, Single Nucleotide - genetics Receptors, Interleukin-6 - genetics Software Genetic mapping Human Interleukin 6 Cartography Allele Admixture Genetics Biological receptor
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