Rohitukine content across the geographical distribution of Dysoxylum binectariferum Hook F. and its natural derivatives as potential sources of CDK inhibitors

Dysoxylum binectariferum is an important medicinal plant distributed in the Western Ghats of India. The species has gained international importance for its anticancer component, rohitukine, a chromone alkaloid. Flavopiridol, P-276-00 and IIIM-290 are the derivatives of rohitukine in clinical trials...

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Bibliographic Details

Published in:	Heliyon Vol. 9; no. 2; p. e13469
Main Authors:	Varun, E., Bhakti, K., Aishwarya, K., Suraj, R Hosur, Jagadish, M.R., Mohana Kumara, P.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-02-2023 Elsevier
Subjects:	CDKs Dysoxylum binectariferum HPLC Pharmacokinetic potential Rohitukine Pharmacokinetic potential Dysoxylum binectariferum Rohitukine CDKs HPLC
Online Access:	Get full text
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