The cell surface proteoglycan from mouse mammary epithelial cells bears chondroitin sulfate and heparan sulfate glycosaminoglycans

The cell surface proteoglycan fraction isolated by mild trypsin treatment of NMuMG mouse mammary epithelial cells contains largely heparan sulfate, but also 15-24% chondroitin sulfate glycosaminoglycans. We conclude that this fraction contains a unique hybrid proteoglycan bearing both heparan sulfat...

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Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 260; no. 20; pp. 11046 - 11052
Main Authors:	Rapraeger, A, Jalkanen, M, Endo, E, Koda, J, Bernfield, M
Format:	Journal Article
Language:	English
Published:	Bethesda, MD Elsevier Inc 15-09-1985 American Society for Biochemistry and Molecular Biology
Subjects:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Cell Line Cell Membrane - analysis Chondroitin - analogs & derivatives Chondroitin Sulfate Proteoglycans - analysis Chondroitin Sulfates - analysis Collagen - metabolism Dithiothreitol - pharmacology Epithelium - analysis Fundamental and applied biological sciences. Psychology Glycosaminoglycans - analysis Heparan Sulfate Proteoglycans Heparitin Sulfate - analysis Inorganic compounds Mammary Glands, Animal - analysis Mammary Glands, Animal - metabolism Mice Molecular Weight Nitrous Acid - pharmacology Other biological molecules Proteoglycans - analysis Proteoglycans - isolation & purification Proteoglycans - metabolism Proteoglycan Cell culture Vertebrata Mammalia Mouse Molecular structure Rodentia Epithelial cell Glycoproteins Mammary gland Cell surface
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