B7-H3/CD276 and small-cell lung cancer: What's new?

•B7-H3, also known as CD276, is a member of the B7 family overexpressed in tumor tissues, including SCLC.•The overexpression of B7-H3 is often correlated with worse survival.•B7-H3 could represent an attractive target for antibody-based immunotherapy.•Combining B7-H3 and other immune checkpoint inhi...

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Bibliographic Details
Published in:Translational oncology Vol. 39; p. 101801
Main Authors: Fabrizio, Federico Pio, Muscarella, Lucia Anna, Rossi, Antonio
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-01-2024
Neoplasia Press
Elsevier
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Online Access:Get full text
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