Matrix metalloproteinases and tissue remodeling in hypertrophic cardiomyopathy

Background Hypertrophic cardiomyopathy (HCM) is defined by the presence of unexplained left ventricular hypertrophy, myocyte disarray, and interstitial fibrosis. An increase in extracellular matrix produces interstitial fibrosis, by raised amounts of collagen type I/III. Regions of myocardial late g...

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Bibliographic Details
Published in:	The American heart journal Vol. 156; no. 1; pp. 85 - 91
Main Authors:	Roldán, Vanessa, MD, PhD, Marín, Francisco, MD, PhD, Gimeno, Juan R., MD, PhD, Ruiz-Espejo, Francisco, MD, González, Josefa, MD, Feliu, Eloisa, MD, PhD, García-Honrubia, Antonio, MD, Saura, Daniel, MD, de la Morena, Gonzalo, MD, Valdés, Mariano, PhD, Vicente, Vicente, PhD
Format:	Journal Article
Language:	English
Published:	New York, NY Mosby, Inc 01-07-2008 Elsevier Elsevier Limited
Subjects:	Adult Biological and medical sciences Biomarkers - blood Cardiac arrhythmia Cardiology. Vascular system Cardiomyopathy Cardiomyopathy, Hypertrophic - blood Cardiomyopathy, Hypertrophic - diagnosis Cardiomyopathy, Hypertrophic - mortality Cardiovascular Case-Control Studies Cohort Studies Collagen Enzyme-Linked Immunosorbent Assay Female Fitness equipment Gadolinium DTPA Heart Heart attacks Heart failure Hospitals Humans Image Enhancement Magnetic Resonance Imaging Male Matrix Metalloproteinase 1 - blood Matrix Metalloproteinase 2 - blood Matrix Metalloproteinase 9 - blood Matrix Metalloproteinases - blood Medical sciences Middle Aged Multivariate analysis Myocarditis. Cardiomyopathies Probability Prognosis Reference Values Risk factors Sensitivity and Specificity Severity of Illness Index Software Survival Analysis Tissue Inhibitor of Metalloproteinase-1 - blood Ventricular Remodeling - physiology Vascular remodeling Peptidases Tissue Enzyme Heart disease Hypertrophic cardiomyopathy Hydrolases Metalloendopeptidases Cardiovascular disease Circulatory system Cardiology Myocardial disease
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