Demonstration of a Na+/H+ exchange activity in purified canine cardiac sarcolemmal vesicles

Purified canine cardiac sarcolemmal membrane vesicles exhibit a sodium ion for proton exchange activity (Na+/H+ exchange). Na+/H+ exchange was demonstrated both by measuring rapid 22Na uptake into sarcolemmal vesicles in response to a transmembrane H+ gradient and by following H+ transport in respon...

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Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 260; no. 8; pp. 4869 - 4876
Main Authors:	Seiler, S M, Cragoe, E J, Jones, L R
Format:	Journal Article
Language:	English
Published:	Bethesda, MD Elsevier Inc 25-04-1985 American Society for Biochemistry and Molecular Biology
Subjects:	Alamethicin - pharmacology Animals Biological and medical sciences Carrier Proteins - metabolism Cell physiology Dogs Fundamental and applied biological sciences. Psychology Hydrogen-Ion Concentration Kinetics Membrane Potentials Molecular and cellular biology Muscle contraction Myocardium - metabolism Quinacrine - pharmacology Quinidine - pharmacology Quinuclidinyl Benzilate - metabolism Sarcolemma - metabolism Sodium - metabolism Sodium-Hydrogen Exchangers Subcellular Fractions - metabolism Heart Sarcolemma Vesicle Fissipedia Carnivora Monovalent cation Ion transport Muscle contraction Vertebrata Regulation(control) Mammalia Sodium Animal Myocardium Proton Ion exchange Dog
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