Celiac disease in patients with type 1 diabetes: a condition with distinct changes in intestinal immunity?

Two common chronic childhood diseases—celiac disease (CD) and type 1 diabetes (T1D)—result from complex pathological mechanisms where genetic susceptibility, environmental exposure, alterations in intestinal permeability and immune responses play central roles. In this study, we investigated whether...

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Bibliographic Details
Published in:	Cellular & molecular immunology Vol. 8; no. 2; pp. 150 - 156
Main Authors:	Uibo, Raivo, Panarina, Marina, Teesalu, Kaupo, Talja, Ija, Sepp, Epp, Utt, Meeme, Mikelsaar, Marika, Heilman, Kaire, Uibo, Oivi, Vorobjova, Tamara
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01-03-2011 Nature Publishing Group
Subjects:	Adolescent Animals Antibodies Antibodies, Bacterial - immunology Antigens Autoantibodies Bacterial Proteins - immunology Bifidobacterium - immunology Biomedical and Life Sciences Biomedicine Cattle Celiac disease Celiac Disease - complications Celiac Disease - immunology Celiac Disease - microbiology Celiac Disease - pathology Child Child, Preschool Children Diabetes Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - complications Diabetes Mellitus, Type 1 - immunology Diabetes Mellitus, Type 1 - microbiology Diabetes Mellitus, Type 1 - pathology Environmental factors Female Forkhead protein Forkhead Transcription Factors - genetics Forkhead Transcription Factors - metabolism Foxp3 protein Gene Expression Regulation Gliadin - immunology GTP-Binding Proteins - genetics GTP-Binding Proteins - metabolism Humans Immunity Immunity (Disease) Immunity - immunology Immunoglobulin A Immunoglobulin A - immunology Immunoglobulin G Immunoglobulin G - immunology Immunology Immunoregulation Infant Intestinal Mucosa - enzymology Intestinal Mucosa - pathology Intestines - immunology Intestines - pathology Lactoglobulins - immunology Lymphocytes T Male Medical Microbiology Membrane Proteins - genetics Membrane Proteins - metabolism Microbiology mRNA Mucosa Permeability Phosphoproteins - genetics Phosphoproteins - metabolism research-article RNA, Messenger - genetics RNA, Messenger - metabolism Serum levels Small intestine Tight junctions Transglutaminase 2 Transglutaminases - genetics Transglutaminases - metabolism Vaccine Zonula Occludens-1 Protein β-Lactoglobulin celiac disease immunoregulation type 1 diabetes intestinal mucosa autoimmunity
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