Melanocortin 1 Receptor: Structure, Function, and Regulation

The melanocortin 1 receptor (MC1R) is a melanocytic Gs protein coupled receptor that regulates skin pigmentation, UV responses, and melanoma risk. It is a highly polymorphic gene, and loss of function correlates with a fair, UV-sensitive, and melanoma-prone phenotype due to defective epidermal melan...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 7; p. 95
Main Authors:	Wolf Horrell, Erin M, Boulanger, Mary C, D'Orazio, John A
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 31-05-2016
Subjects:	DNA Repair Genetics melanin melanocortin melanocortin receptor Melanocytes MC1R melanocyte ASIP melanoma βD3 DNA repair ATR melanocortin
Online Access:	Get full text
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