Experimental Gestational Diabetes Mellitus Induces Blunted Vasoconstriction and Functional Changes in the Rat Aorta

Diabetic conditions increase vascular reactivity to angiotensin II in several studies but there are scarce reports on cardiovascular effects of hypercaloric diet (HD) induced gestational diabetes mellitus (GDM), so the objective of this work was to determine the effects of HD induced GDM on vascular...

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Bibliographic Details
Published in:	BioMed research international Vol. 2014; no. 2014; pp. 1 - 11
Main Authors:	Bracho-Valdés, Ismael, Ibarra-Barajas, Maximiliano, Villanueva, Cleva, Tufiño, Cecilia, Bobadilla-Lugo, Rosa Amalia
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Publishing Corporation 01-01-2014 John Wiley & Sons, Inc Hindawi Limited
Subjects:	Angiotensin II - administration & dosage Animals Aorta Diabetes in pregnancy Diabetes Mellitus, Experimental - chemically induced Diabetes Mellitus, Experimental - physiopathology Diabetes, Gestational - chemically induced Diabetes, Gestational - drug therapy Diabetes, Gestational - physiopathology Female Glucose Humans Insulin Insulin resistance Losartan - administration & dosage Obesity Phenylephrine - administration & dosage Physiological aspects Pregnancy Rats Rodents Vasoconstriction Vasoconstriction - drug effects Vasoconstrictor Agents - administration & dosage Vasodilation - drug effects
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