Relationship Between Depression and Subtypes of Early Life Stress in Adult Psychiatric Patients
Numerous studies have researched the aggravating and maintainer effect of Early Life Stress in patients adults with psychiatric disorders. This study examined the relationship between depression and subtypes of early life stress among 81 psychiatric patients treated at the inpatient Day Hospital Uni...
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| Published in: | Frontiers in psychiatry Vol. 10; p. 19 |
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| Abstract | Numerous studies have researched the aggravating and maintainer effect of Early Life Stress in patients adults with psychiatric disorders. This study examined the relationship between depression and subtypes of early life stress among 81 psychiatric patients treated at the inpatient Day Hospital Unit of a University General Hospital. Psychiatric diagnosis was confirmed according to the MINI International Neuropsychiatric Interview (MINI). The Childhood Trauma Questionnaire (CTQ) was used for evaluating as retrospective assessment of the presence of ELS on these patients, and we also evaluated the severity of hopelessness with the Beck Hopelessness Scale (BHS). Our results suggested that the occurrence of depression in adulthood is related to situations of emotional abuse, sexual, and physical neglect during childhood. The analysis between depression and childhood emotional abuse was significant after a multiple logistic regression analysis OR (IC 95%): 4.4 (1.7-11.2), even accounting for gender adjusted OR [AOR] 4.0; (IC 1.5-10.5); psychiatry family history AOR 3.8 (1.4-10.5); previous suicide attempted AOR 3.7; (1.4-10.5) and Hopelessness AOR 3.2 (1.11-9.4). Thus, these findings demonstrate emotional abuse as a significant risk factor to be part of the mechanism involved in the pathogenesis of depression related to early life stress. |
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| AbstractList | Numerous studies have researched the aggravating and maintainer effect of Early Life Stress in patients adults with psychiatric disorders. This study examined the relationship between depression and subtypes of early life stress among 81 psychiatric patients treated at the inpatient Day Hospital Unit of a University General Hospital. Psychiatric diagnosis was confirmed according to the MINI International Neuropsychiatric Interview (MINI). The Childhood Trauma Questionnaire (CTQ) was used for evaluating as retrospective assessment of the presence of ELS on these patients, and we also evaluated the severity of hopelessness with the Beck Hopelessness Scale (BHS). Our results suggested that the occurrence of depression in adulthood is related to situations of emotional abuse, sexual, and physical neglect during childhood. The analysis between depression and childhood emotional abuse was significant after a multiple logistic regression analysis OR (IC 95%): 4.4 (1.7–11.2), even accounting for gender adjusted OR [AOR] 4.0; (IC 1.5–10.5); psychiatry family history AOR 3.8 (1.4–10.5); previous suicide attempted AOR 3.7; (1.4–10.5) and Hopelessness AOR 3.2 (1.11–9.4). Thus, these findings demonstrate emotional abuse as a significant risk factor to be part of the mechanism involved in the pathogenesis of depression related to early life stress. |
| Author | Reisdorfer, Emilene Juruena, Mario Francisco Tofoli, Sandra Marcia de Carvalho Martins-Monteverde, Camila Maria Severi Padovan, Thalita Baes, Cristiane Von Werne |
| AuthorAffiliation | 1 Stress and Affective Disorders Programme, University of São Paulo , São Paulo , Brazil 3 Centre for Affective Disorders, Department Psychological Medicine, King's College London , London , United Kingdom 2 School of Community and Health Studies, Centennial College , Toronto, ON , Canada |
| AuthorAffiliation_xml | – name: 1 Stress and Affective Disorders Programme, University of São Paulo , São Paulo , Brazil – name: 2 School of Community and Health Studies, Centennial College , Toronto, ON , Canada – name: 3 Centre for Affective Disorders, Department Psychological Medicine, King's College London , London , United Kingdom |
| Author_xml | – sequence: 1 givenname: Camila Maria Severi surname: Martins-Monteverde fullname: Martins-Monteverde, Camila Maria Severi organization: Stress and Affective Disorders Programme, University of São Paulo, São Paulo, Brazil – sequence: 2 givenname: Cristiane Von Werne surname: Baes fullname: Baes, Cristiane Von Werne organization: Stress and Affective Disorders Programme, University of São Paulo, São Paulo, Brazil – sequence: 3 givenname: Emilene surname: Reisdorfer fullname: Reisdorfer, Emilene organization: School of Community and Health Studies, Centennial College, Toronto, ON, Canada – sequence: 4 givenname: Thalita surname: Padovan fullname: Padovan, Thalita organization: Stress and Affective Disorders Programme, University of São Paulo, São Paulo, Brazil – sequence: 5 givenname: Sandra Marcia de Carvalho surname: Tofoli fullname: Tofoli, Sandra Marcia de Carvalho organization: Stress and Affective Disorders Programme, University of São Paulo, São Paulo, Brazil – sequence: 6 givenname: Mario Francisco surname: Juruena fullname: Juruena, Mario Francisco organization: Centre for Affective Disorders, Department Psychological Medicine, King's College London, London, United Kingdom |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30804815$$D View this record in MEDLINE/PubMed |
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| ContentType | Journal Article |
| Copyright | Copyright © 2019 Martins-Monteverde, Baes, Reisdorfer, Padovan, Tofoli and Juruena. 2019 Martins-Monteverde, Baes, Reisdorfer, Padovan, Tofoli and Juruena |
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| Keywords | depressive disorder childhood trauma emotional abuse subtypes of early life stress early life stress neglect |
| Language | English |
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| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Edited by: Diogo Telles-Correia, Universidade de Lisboa, Portugal Reviewed by: Liang Gong, Southeast University, China; Alexandre Paim Diaz, Federal University of Santa Catarina, Brazil This article was submitted to Psychopathology, a section of the journal Frontiers in Psychiatry |
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| Title | Relationship Between Depression and Subtypes of Early Life Stress in Adult Psychiatric Patients |
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