Apelin, a New Enteric Peptide: Localization in the Gastrointestinal Tract, Ontogeny, and Stimulation of Gastric Cell Proliferation and of Cholecystokinin Secretion

Apelin is a recently discovered peptide that is the endogenous ligand for the APJ receptor. The aim of this study was to characterize apelin expression (mRNA levels) in the rat gastrointestinal tract and pancreas, to localize distribution of apelin peptide-containing cells in the stomach by immunohi...

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Bibliographic Details
Published in:	Endocrinology (Philadelphia) Vol. 145; no. 3; pp. 1342 - 1348
Main Authors:	Wang, Guiyun, Anini, Younes, Wei, Wei, Qi, Xiang, O’Carroll, Anne-Marie, Mochizuki, Tohru, Wang, Hui-Quin, Hellmich, Mark R, Englander, Ella W, Greeley, George H
Format:	Journal Article
Language:	English
Published:	Bethesda, MD Endocrine Society 01-03-2004 Oxford University Press
Subjects:	Animals Apelin Biological and medical sciences Calcium (intracellular) Calcium ions Calcium Signaling - drug effects Calcium signalling Carrier Proteins - genetics Carrier Proteins - metabolism Carrier Proteins - pharmacology Cell Division - drug effects Cell Division - physiology Cell growth Cell Line Cell proliferation Cholecystokinin Cholecystokinin - secretion Epithelium Female Fetuses Fundamental and applied biological sciences. Psychology Gastrointestinal system Gastrointestinal tract Gene expression Immunohistochemistry In Vitro Techniques Intercellular Signaling Peptides and Proteins Intestine Intracellular Intracellular signalling Kinases Localization Male MAP kinase Mitogen-Activated Protein Kinases - metabolism mRNA Ontogeny Pancreas Peptides Pregnancy Protein kinase C Protein Kinase C - metabolism Rats Rats, Sprague-Dawley RNA, Messenger - analysis Stomach Stomach - cytology Stomach - metabolism Vertebrates: endocrinology Cell proliferation Stomach Peptides Digestive system Stimulation Cholecystokinin Gastrointestinal Localization Neuropeptide Endocrine secretion
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