The COVID-19 Sentinel Schools Network of Catalonia (CSSNC) project: Associated factors to prevalence and incidence of SARS-CoV-2 infection in educational settings during the 2020-2021 academic year

• Published in: PloS one Vol. 17; no. 11; p. e0277764
• Main Authors: Ganem, Fabiana, Bordas, Anna, Folch, Cinta, Alonso, Lucia, Montoro-Fernandez, Marcos, Colom-Cadena, Andreu, Mas, Ariadna, Mendioroz, Jacobo, Asso, Laia, Anton, Andres, Pumarola, Tomàs, González, Maria Victoria, Blanco, Ignacio, Soler-Palacín, Pere, Soriano-Arandes, Antoni, Casabona, Jordi
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17-11-2022; Public Library of Science (PLoS)
• Subjects: Biology and life sciences; Child; Coronaviruses; COVID-19; COVID-19 - epidemiology; COVID-19 vaccines; Cross-Sectional Studies; Data collection; Disease transmission; Epidemics; Epidemiology; Evaluation; Health promotion; Health risks; Humans; Incidence; Infections; Longitudinal studies; Medicine and health sciences; Multivariate analysis; Pandemics; Prevalence; Prevention; Public health; Questionnaires; Risk analysis; Risk factors; Risk perception; SARS-CoV-2; Schools; Seroepidemiologic Studies; Serology; Severe acute respiratory syndrome coronavirus 2; Social Sciences; Sociodemographics; Socioeconomics; Spain - epidemiology; Students; Teaching; Spain; Madrid Spain
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0277764

The Sentinel Schools project was designed to monitor and evaluate the epidemiology of COVID-19 in Catalonia, gathering evidence for health and education policies to inform the development of health protocols and public health interventions to control of SARS-CoV-2 infection in schools. The aim of this study was to estimate the prevalence and incidence of SARS-CoV-2 infections and to identify their determinants among students and staff during February to June in the academic year 2020-2021. We performed two complementary studies, a cross-sectional and a longitudinal component, using a questionnaire to collect nominal data and testing for SARS-CoV-2 detection. We describe the results and perform a univariate and multivariate analysis. The initial crude seroprevalence was 14.8% (95% CI: 13.1-16.5) and 22% (95% CI: 18.3-25.8) for students and staff respectively, and the active infection prevalence was 0.7% (95% CI: 0.3-1) and 1.1% (95% CI: 0.1-2). The overall incidence for persons at risk was 2.73 per 100 person-month and 2.89 and 2.34 per 100 person-month for students and staff, respectively. Socioeconomic, self-reported knowledge, risk perceptions and contact pattern variables were positively associated with the outcome while sanitary measure compliance was negatively associated, the same significance trend was observed in multivariate analysis. In the longitudinal component, epidemiological close contact with SARS-CoV-2 infection was a risk factor for SARS-CoV-2 infection while the highest socioeconomic status level was protective as was compliance with sanitary measures. The small number of active cases detected in these schools suggests a low transmission among children in school and the efficacy of public health measures implemented, at least in the epidemiological scenario of the study period. The major contribution of this study was to provide results and evidence that help analyze the transmission dynamic of SARS-CoV-2 and evaluate the associations between sanitary protocols implemented, and measures to avoid SARS-CoV-2 spread in schools.