A Fucus vesiculosus extract inhibits estrogen receptor activation and induces cell death in female cancer cell lines

We previously reported the anti-estrogenic activity of the brown seaweed, Fucus vesiculosus. The present study aimed to further investigate its anti-estrogenic modes of action and to assess other potentially biologically relevant anti-tumorigenic effects in estrogen receptor (ER)-dependent and -inde...

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Bibliographic Details
Published in:	BMC complementary and alternative medicine Vol. 16; no. 151; p. 151
Main Authors:	Zhang, Jianqing, Riby, Jacques E, Conde, Lucia, Grizzle, William E, Cui, Xiangqin, Skibola, Christine F
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 28-05-2016 BioMed Central
Subjects:	Antineoplastic Agents, Hormonal - pharmacology Apoptosis - drug effects Aromatase - metabolism Autophagy - drug effects Biomarkers - metabolism Bladderwrack Caspases - metabolism Cell death Cell Line, Tumor Cell Survival - drug effects Enzyme Activation - drug effects Estrogen Female Fucus - chemistry Gene Expression - drug effects Humans Influence Physiological aspects Receptors Receptors, Estrogen - antagonists & inhibitors Risk factors Seaweed Anti-estrogenic activity PI3K signaling Fucoidan Autophagy Apoptosis
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