Evolutionary conservation in the hepatitis B virus core structure: comparison of human and duck cores

Background: Hepatitis B virus is a major human pathogen which has been extensively studied, yet its structure is unknown. Cryo-electron microscopy of the viral cores expressed in Escherichia coli or isolated from infected liver provides a means for determining the structure of the hepatitis B nucleo...

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Bibliographic Details
Published in:	Structure (London) Vol. 3; no. 10; pp. 1009 - 1019
Main Authors:	Kenney, John M, Bonsdorff, Carl-Henrik von, Nassal, Michael, Fuller, Stephen D
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 15-10-1995
Subjects:	Animals capsid cryo-electron microscopy Cryopreservation Ducks Epitope Mapping Evolution, Molecular Hepatitis B Core Antigens - immunology Hepatitis B Core Antigens - ultrastructure hepatitis B virus Hepatitis B virus - chemistry Hepatitis B virus - ultrastructure Hepatitis B Virus, Duck - chemistry Hepatitis B Virus, Duck - ultrastructure Humans Image Processing, Computer-Assisted immuno-electron microscopy Liver - virology Microscopy, Electron - methods Models, Molecular Nucleic Acid Conformation Recombinant Proteins - chemistry Recombinant Proteins - immunology three-dimensional reconstruction Viral Core Proteins - chemistry immuno-electron microscopy hepatitis B virus capsid cryo-electron microscopy three-dimensional reconstruction
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