Malignant Pheochromocytoma with Liver Metastasis Treated by Transcatheter Arterial Chemo-Embolization (TACE)

• Published in: Internal Medicine Vol. 49; no. 7; pp. 645 - 651
• Main Authors: Hidaka, Satoshi, Hiraoka, Atsushi, Ochi, Hironori, Uehara, Takahide, Ninomiya, Tomoyuki, Miyamoto, Yasunao, Hasebe, Aki, Tanihira, Tetsuya, Tanabe, Atsushi, Ichiryu, Misa, Nakahara, Hiromasa, Tazuya, Nayu, Ninomiya, Iku, Michitaka, Kojiro
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01-01-2010
• Subjects: Adrenal Gland Neoplasms - diagnostic imaging; Adrenal Gland Neoplasms - therapy; Aged; Antineoplastic Agents - administration & dosage; Chemoembolization, Therapeutic - methods; doxazosin; Female; Humans; Injections, Intra-Arterial; liver metastasis; Liver Neoplasms - diagnostic imaging; Liver Neoplasms - secondary; Liver Neoplasms - therapy; malignant pheochromocytoma; phentolamine; Pheochromocytoma - diagnostic imaging; Pheochromocytoma - secondary; Pheochromocytoma - therapy; TACE; Ultrasonography
• ISSN: 0918-2918; 1349-7235
• DOI: 10.2169/internalmedicine.49.3061

Multiple liver metastatic lesions were shown by computed tomography and scintigraphy with 123I- metaiodobenzylguanidine (MIBG) in a 76-year-old woman 2 years after resection of a pheochromocytoma of the right adrenal gland. Transcatheter arterial chemo-embolization (TACE) was performed for the liver metastasis, with blood pressure strictly controlled by administration of doxazosin and phentolamine for the prevention of hypertensive crisis after TACE. There were no severe adverse events associated with the treatment, and the number and size of the lesions were decreased. TACE with strict blood pressure control was an effective and safe therapy for multiple liver metastatic lesions related to malignant pheochromocytoma.