Sequence analysis of the major outer membrane protein gene of an ovine abortion strain of Chlamydia psittaci

• Published in: FEMS microbiology letters Vol. 53; no. 1-2; p. 153
• Main Authors: Herring, A J, Tan, T W, Baxter, S, Inglis, N F, Dunbar, S
• Format: Journal Article
• Language: English
• Published: England 01-11-1989
• Subjects: Abortion, Veterinary - microbiology; Amino Acid Sequence; Animals; Bacterial Outer Membrane Proteins - genetics; Base Sequence; Blotting, Southern; Chlamydophila psittaci - classification; Chlamydophila psittaci - genetics; Female; Molecular Sequence Data; Pregnancy; Psittacosis - microbiology; Psittacosis - veterinary; Sequence Homology, Nucleic Acid; Sheep; Sheep Diseases - microbiology
• ISSN: 0378-1097
• DOI: 10.1111/j.1574-6968.1989.tb03614.x

The major outer membrane protein (MOMP) gene from an ovine abortion strain of Chlamydia psittaci (S26/3) has been cloned and sequenced. The gene shows the features of other chlamydial MOMPs but comparison with the previously reported sequence for the ovine abortion isolate A22/M has revealed substantial sequence divergence which is clustered into the same four intramolecular regions as the sequence variation found between C. trachomatis serovars. Subsequent restriction enzyme analysis of A22/M DNA has shown that it has an avian-type genomic profile and thus the comparison is between types rather than between strains.