Embryonic--Fetal Erythroid Characteristics of a Human Leukemic Cell Line

We have studied a number of cell surface, enzyme, and protein markers in the human leukemic K562 cell line. We have confirmed previous observations that these cells accumulate human embryonic hemoglobins after exposure to hemin. In addition, our results demonstrated that these cells possess in their...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 77; no. 6; pp. 3509 - 3513
Main Authors:	Benz, Edward J., Murnane, Mary J., Tonkonow, Barry L., Berman, Brian W., Mazur, Eric M., Cavallesco, Cesira, Jenko, Trina, Snyder, Edwin L., Forget, Bernard G., Hoffman, Ronald
Format:	Journal Article
Language:	English
Published:	United States National Academy of Sciences of the United States of America 01-06-1980 National Acad Sciences
Subjects:	Antigens, Surface - analysis B lymphocytes Cell Differentiation Cell Line Cell lines Cells Complementary DNA Erythrocytes Erythrocytes - pathology Erythroid cells Fetal Blood Gels Hematopoietic Stem Cells - pathology Hemin - pharmacology Hemoglobins Hemoglobins - biosynthesis Humans Isoenzymes K562 cells L-Lactate Dehydrogenase - analysis Leukemia, Myeloid - immunology Leukemia, Myeloid - metabolism Leukemia, Myeloid - pathology Messenger RNA RNA, Messenger - analysis
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