NEW BOWEL PREPARATION TECHNIQUE FOR COLONOSCOPY: CLINICAL TRIAL COMPARING AQUANET AND MANNITOL
Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem. To analyze the quality of a new inte...
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| Published in: | Arquivos brasileiros de cirurgia digestiva : ABCD Vol. 31; no. 3; p. e1393 |
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| Main Authors: | , , , , , , |
| Format: | Journal Article |
| Language: | English |
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Brazil
Colégio Brasileiro de Cirurgia Digestiva
16-08-2018
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| Abstract | Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem.
To analyze the quality of a new intestinal preparation technique, Aquanet EC-2000®, compared to oral Mannitol solution.
This prospective longitudinal study enrolled 200 patients with indication for colonoscopy. The sample was randomly allocated to two groups of 100; one group received Aquanet EC-2000® to prepare for colonoscopy and the other Mannitol solution. The Boston scale was used to analyze the results.
As expected both preparations produced similar results with the bowel cleansing of the different regions of the colon being classified as Boston scale 3 (excellent) in most patients (p>0.05).
The results of bowel preparation using Aquanet EC-2000® were similar to using Mannitol solution. |
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| AbstractList | ABSTRACT Background: Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem. Aim: To analyze the quality of a new intestinal preparation technique, Aquanet EC-2000®, compared to oral Mannitol solution. Methods: This prospective longitudinal study enrolled 200 patients with indication for colonoscopy. The sample was randomly allocated to two groups of 100; one group received Aquanet EC-2000® to prepare for colonoscopy and the other Mannitol solution. The Boston scale was used to analyze the results. Results: As expected both preparations produced similar results with the bowel cleansing of the different regions of the colon being classified as Boston scale 3 (excellent) in most patients (p>0.05). Conclusion: The results of bowel preparation using Aquanet EC-2000® were similar to using Mannitol solution.
RESUMO Racional: Cinquenta e cinco por cento dos norte-americanos entre 50-65 anos fazem colonoscopia. Acima de 65 anos o número foi de 64%. No Brasil, estima-se crescente aumento da população submetida à colonoscopia, apesar da preparação inadequada ainda ser um grande problema. Objetivo: Analisar e comparar a qualidade do novo método de preparo intestinal por meio do Aquanet EC-2000® frente ao uso de solução oral de Manitol. Método: Por randomização 200 pacientes foram divididos em dois grupos de 100. Um recebeu Aquanet EC-2000® e o outro Manitol. O presente estudo seguiu modelo prospectivo longitudinal por meio da seleção de 200 pacientes com indicação à colonoscopia, formando dois grupos de 100. Para analisar os resultados foi utilizada a escala de Boston. Resultados: Ambos os preparos foram estatisticamente significativos com p<0,05. A escala 3 de Boston foi a mais frequente para ambos os métodos.Além disso, na estatística aplicada às diferentes regiões do cólon para ambos os procedimentos as proporções observadas concordaram com o esperado (3-excelente). Conclusão: Os resultados do preparo intestinal utilizando Aquanet EC-2000® foram semelhantes aos do Manitol. Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem. To analyze the quality of a new intestinal preparation technique, Aquanet EC-2000®, compared to oral Mannitol solution. This prospective longitudinal study enrolled 200 patients with indication for colonoscopy. The sample was randomly allocated to two groups of 100; one group received Aquanet EC-2000® to prepare for colonoscopy and the other Mannitol solution. The Boston scale was used to analyze the results. As expected both preparations produced similar results with the bowel cleansing of the different regions of the colon being classified as Boston scale 3 (excellent) in most patients (p>0.05). The results of bowel preparation using Aquanet EC-2000® were similar to using Mannitol solution. ABSTRACT Background: Fifty-five percent of Americans aged 50-65 are submitted to colonoscopy. For over 65-year, this number increases to 64%. In Brazil, it is forecast that the population submitted to colonoscopy will grow, even though inadequate preparation is still a major problem. Aim: To analyze the quality of a new intestinal preparation technique, Aquanet EC-2000®, compared to oral Mannitol solution. Methods: This prospective longitudinal study enrolled 200 patients with indication for colonoscopy. The sample was randomly allocated to two groups of 100; one group received Aquanet EC-2000® to prepare for colonoscopy and the other Mannitol solution. The Boston scale was used to analyze the results. Results: As expected both preparations produced similar results with the bowel cleansing of the different regions of the colon being classified as Boston scale 3 (excellent) in most patients (p>0.05). Conclusion: The results of bowel preparation using Aquanet EC-2000® were similar to using Mannitol solution. |
| Author | Kaiser-Júnior, Roberto Luiz Zotarelli-Filho, Idiberto José DE-Oliveira, Vera Lúcia Campo, Juan Carlos Ochoa Flamini-Júnior, Mário DE-Quadros, Luiz Gustavo Faria, Mikaell Alexandre Gouvea |
| AuthorAffiliation | 3 Faculty of Medicine of the ABC, Endoscopy, Santo André, SP 1 Kaiser Clinic and Hospital, Endoscopy and Colonoscopy, São José do Rio Preto, SP 4 Faculty of Medicine, Unilago, Colonoscopy, São José do Rio Preto, SP, Brasil 2 Hospital Beneficência Portuguesa, Colonoscopy, São José do Rio Preto, SP |
| AuthorAffiliation_xml | – name: 3 Faculty of Medicine of the ABC, Endoscopy, Santo André, SP – name: 1 Kaiser Clinic and Hospital, Endoscopy and Colonoscopy, São José do Rio Preto, SP – name: 4 Faculty of Medicine, Unilago, Colonoscopy, São José do Rio Preto, SP, Brasil – name: 2 Hospital Beneficência Portuguesa, Colonoscopy, São José do Rio Preto, SP |
| Author_xml | – sequence: 1 givenname: Roberto Luiz surname: Kaiser-Júnior fullname: Kaiser-Júnior, Roberto Luiz organization: Hospital Beneficência Portuguesa, Colonoscopy, São José do Rio Preto, SP – sequence: 2 givenname: Luiz Gustavo surname: DE-Quadros fullname: DE-Quadros, Luiz Gustavo organization: Faculty of Medicine of the ABC, Endoscopy, Santo André, SP – sequence: 3 givenname: Mário surname: Flamini-Júnior fullname: Flamini-Júnior, Mário organization: Hospital Beneficência Portuguesa, Colonoscopy, São José do Rio Preto, SP – sequence: 4 givenname: Mikaell Alexandre Gouvea surname: Faria fullname: Faria, Mikaell Alexandre Gouvea organization: Faculty of Medicine, Unilago, Colonoscopy, São José do Rio Preto, SP, Brasil – sequence: 5 givenname: Juan Carlos Ochoa surname: Campo fullname: Campo, Juan Carlos Ochoa organization: Kaiser Clinic and Hospital, Endoscopy and Colonoscopy, São José do Rio Preto, SP – sequence: 6 givenname: Vera Lúcia surname: DE-Oliveira fullname: DE-Oliveira, Vera Lúcia organization: Kaiser Clinic and Hospital, Endoscopy and Colonoscopy, São José do Rio Preto, SP – sequence: 7 givenname: Idiberto José surname: Zotarelli-Filho fullname: Zotarelli-Filho, Idiberto José organization: Hospital Beneficência Portuguesa, Colonoscopy, São José do Rio Preto, SP |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/30133685$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Administration, Oral Cathartics - administration & dosage Clinical protocols Clinical trial Colonoscopy Comparative study Female Humans Longitudinal Studies Male Mannitol - administration & dosage Middle Aged Original Preoperative Care - instrumentation Preoperative Care - methods Propensity score Prospective Studies Therapeutic Irrigation |
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| Title | NEW BOWEL PREPARATION TECHNIQUE FOR COLONOSCOPY: CLINICAL TRIAL COMPARING AQUANET AND MANNITOL |
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