CYTOPLASMIC-MEMBRANE EGFR PREDICTS EXPANDED RAS MUTATION STATUS IN COLORECTAL CARCINOMAS?

Inhibitors of the epidermal growth factor (EGFR) represent an effective therapeutic option for patients with metastatic colorectal carcinoma, free of activating mutations in KRAS and NRAS. However, the research of mutations is of high cost and scarcely accessible. The expression of the EGFR by immun...

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Bibliographic Details

Published in:	Arquivos brasileiros de cirurgia digestiva : ABCD Vol. 34; no. 1; p. e1574
Main Authors:	Pinto, Thiago David Alves, Alves, Thaís David das Neves, Pinto, Sebastião Alves, Oliveira, Enio Chaves
Format:	Journal Article
Language:	English
Published:	Brazil Colégio Brasileiro de Cirurgia Digestiva 01-01-2021
Subjects:	Colorectal cancer Colorectal Neoplasms - genetics Epidermal Growth Factor Epidermal growth factor receptor ErbB Receptors - genetics Humans Mutation Original Proto-Oncogene Proteins B-raf - genetics Ras genes
Online Access:	Get full text
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